Uutta viruksista: IFITM1,2,3 ja mycobaterium Esimerkki bakteerien puolelta

söndag 1 mars 2020

IFITM1,2,3 ja mycobaterium Esimerkki bakteerien puolelta

https://www.sciencedirect.com/science/article/pii/S2211124715010736
ViragaHaridas¹ Luke D.Jasenosky¹ James V.Falvo¹ Anne E.Goldfeld¹

https://doi.org/10.1016/j.celrep.2015.09.048 Get rights and content

Highlights

•: Mycobacterium tuberculosis (MTb) and TLR2/4 signaling induce IFITM1–3 transcription
•: IFITM1–3 restrict intracellular growth of MTb
•: IFITM3 co-localizes with MTb, especially in late phagosomes
•: IFITM3 enhances intracellular endosomal acidification in MTb-infected cells

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