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torsdag 5 mars 2020

APOBEC ja Nidovirales?

https://www.ncbi.nlm.nih.gov/pubmed/?term=nidovirales%2C+ABOBEC

Like HIV-1 NC, the SARS-CoV or HCoV-229E N-associated with hA3G depends on the presence of RNA, with the first linker region essential for hA3G packaging into both HIV-1 and SARS-CoV VLPs. The results raise the possibility that hA3G is capable of associating with different species of viral structural proteins through a potentially common, RNA-mediated mechanism.

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