mat_peptide 6799..7096
/product="2'-O-ribose methyltransferase"
/note="nsp16; 2'-o-MT; produced by pp1ab only"
/protein_id="YP_009725311.1"
/calculated_mol_wt=33324..
FEATURES Location/Qualifiers
source 1..298
/organism="Severe acute respiratory syndrome coronavirus
2"
/isolate="Wuhan-Hu-1"
/host="Homo sapiens"
/db_xref="taxon:2697049"
/country="China"
/collection_date="Dec-2019"
Protein 1..298
/product="2'-O-ribose methyltransferase"
/note="nsp16; 2'-o-MT; produced by pp1ab only"
/calculated_mol_wt=33324
Precursor 1..298
/derived_from="YP_009724389.1:6799..7096"
ORIGIN
1 ssqawqpgva mpnlykmqrm llekcdlqny gdsatlpkgi mmnvakytql cqylntltla
61 vpynmrvihf gagsdkgvap gtavlrqwlp tgtllvdsdl ndfvsdadst ligdcatvht
121 ankwdliisd mydpktknvt kendskegff tyicgfiqqk lalggsvaik itehswnadl
181 yklmghfaww tafvtnvnas sseafligcn ylgkpreqid gyvmhanyif wrntnpiqls
241 syslfdmskf plklrgtavm slkegqindm ilsllskgrl iirennrvvi ssdvlvnn
//
sars2 Swiss model
YP_009725311.1 (298 residues)2'-O-ribose methyltransferase (nsp16):
Methyltransferase that mediates
mRNA cap 2'-O-ribose methylation to the 5'-cap structure of viral
mRNAs. N7-methyl guanosine cap is a prerequisite for binding of nsp16.
Therefore plays an essential role in viral mRNAs cap methylation which
is essential to evade immune system.
High quality models are available. Hetero-oligomeric complex with nsp10 is
available in hetero section.
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