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onsdag 4 mars 2020

COVID-19 nsp3 sekvenssi

LOCUS       YP_009725299            1945 aa            linear   VRL 28-JAN-2020
DEFINITION  nsp3 [Severe acute respiratory syndrome coronavirus 2].
ACCESSION   YP_009725299
VERSION     YP_009725299.1
DBLINK      BioProject: PRJNA485481
DBSOURCE    REFSEQ: accession YP_009724389.1
KEYWORDS    RefSeq.
SOURCE      Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
  ORGANISM  Severe acute respiratory syndrome coronavirus 2
            Viruses; Riboviria; Nidovirales; Cornidovirineae; Coronaviridae;
            Orthocoronavirinae; Betacoronavirus; Sarbecovirus.
REFERENCE   1  (residues 1 to 1945)
  AUTHORS   Wu,F., Zhao,S., Yu,B., Chen,Y.-M., Wang,W., Hu,Y., Song,Z.-G.,
            Tao,Z.-W., Tian,J.-H., Pei,Y.-Y., Yuan,M.L., Zhang,Y.-L.,
            Dai,F.-H., Liu,Y., Wang,Q.-M., Zheng,J.-J., Xu,L., Holmes,E.C. and
            Zhang,Y.-Z.
  TITLE     A novel coronavirus associated with a respiratory disease in Wuhan
            of Hubei province, China
  JOURNAL   Unpublished
REFERENCE   2  (residues 1 to 1945)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-JAN-2020) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 1945)
  AUTHORS   Wu,F., Zhao,S., Yu,B., Chen,Y.-M., Wang,W., Hu,Y., Song,Z.-G.,
            Tao,Z.-W., Tian,J.-H., Pei,Y.-Y., Yuan,M.L., Zhang,Y.-L.,
            Dai,F.-H., Liu,Y., Wang,Q.-M., Zheng,J.-J., Xu,L., Holmes,E.C. and
            Zhang,Y.-Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JAN-2020) Shanghai Public Health Clinical Center &
            School of Public Health, Fudan University, Shanghai, China
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to
            YP_009724389:819-2763.
            Annotation was added using homology to SARSr-CoV NC_004718.3. If
            you have questions or suggestions, please email us at
            info@ncbi.nlm.nih.gov and include the accession number
            NC_045512.##Find all other Wuhan seafood market pneumonia virus
            (2019-nCov) sequences at
            https://www.ncbi.nlm.nih.gov/genbank/2019-ncov-seqs/
            
            ##Assembly-Data-START##
            Assembly Method       :: Megahit v. V1.1.3
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..1945
                     /organism="Severe acute respiratory syndrome coronavirus
                     2"
                     /isolate="Wuhan-Hu-1"
                     /host="Homo sapiens"
                     /db_xref="taxon:2697049"
                     /country="China"
                     /collection_date="Dec-2019"
     Protein         1..1945
                     /product="nsp3"
                     /note="former nsp1; conserved domains are: N-terminal
                     acidic (Ac), predicted phosphoesterase, papain-like
                     proteinase, Y-domain, transmembrane domain 1 (TM1),
                     adenosine diphosphate-ribose 1''-phosphatase (ADRP);
                     produced by both pp1a and pp1ab"
                     /calculated_mol_wt=217254
     Precursor       1..1945
                     /derived_from="YP_009724389.1:819..2763"
ORIGIN      
        1 aptkvtfgdd tvievqgyks vnitfelder idkvlnekcs aytvelgtev nefacvvada
       61 viktlqpvse lltplgidld ewsmatyylf desgefklas hmycsfyppd edeeegdcee
      121 eefepstqye ygteddyqgk plefgatsaa lqpeeeqeed wldddsqqtv gqqdgsednq
      181 tttiqtivev qPqlemeltp vvqtievnsf sgylkltdnv yiknadivee akkvkptvvv
      241 naanvylkhg ggvagalnka tnnamqvesd dyiatngplk vggscvlsgh nlakhclhvv
      301 gpnvnkgedi qllksayenf nqhevllapl lsagifgadp ihslrvcvdt vrtnvylavf
      361 dknlydklvs sflemksekq veqkiaeipk eevkpfites kpsveqrkqd dkkikacvee
      421 vtttleetkf ltenlllyid ingnlhpdsa tlvsdiditf lkkdapyivg dvvqegvlta
      481 vviptkkagg ttemlakalr kvptdnyitt ypgqglngyt veeaktvlkk cksafyilps
      541 iisnekqeil gtvswnlrem lahaeetrkl mpvcvetkai vstiqrkykg ikiqegvvdy
      601 garfyfytsk ttvaslintl ndlnetlvtm plgyvthgln leeaarymrs lkvpatvsvs
      661 spdavtayng yltsssktpe ehfietisla gsykdwsysg qstqlgiefl krgdksvyyt
      721 snpttfhldg evitfdnlkt llslrevrti kvfttvdnin lhtqvvdmsm tygqqfgpty
      781 ldgadvtkik phnshegktf yvlpnddtlr veafeyyhtt dpsflgryms alnhtkkwky
      841 pqvngltsik wadnncylat alltlqqiel kfnppalqda yyrarageaa nfcalilayc
      901 nktvgelgdv retmsylfqh anldsckrvl nvvcktcgqq qttlkgveav mymgtlsyeq
      961 fkkgvqipct cgkqatkylv qqespfvmms appaqyelkh gtftcaseyt gnyqcghykh
     1021 itsketlyci dgalltksse ykgpitdvfy kensytttik pvtykldgvv cteidpkldn
     1081 yykkdnsyft eqpidlvpnq pypnasfdnf kfvcdnikfa ddlnqltgyk kpasrelkvt
     1141 ffpdlngdvv aidykhytps fkkgakllhk pivwhvnnat nkatykpntw circlwstkp
     1201 vetsnsfdvl ksedaqgmdn lacedlkpvs eevvenptiq kdvlecnvkt tevvgdiilk
     1261 pannslkite evghtdlmaa yvdnssltik kpnelsrvlg lktlathgla avnsvpwdti
     1321 anyakpflnk vvstttnivt rclnrvctny mpyfftlllq lctftrstns rikasmptti
     1381 akntvksvgk fcleasfnyl kspnfsklin iiiwflllsv clgsliysta algvlmsnlg
     1441 mpsyctgyre gylnstnvti atyctgsipc svclsgldsl dtypsletiq itissfkwdl
     1501 tafglvaewf layilftrff yvlglaaimq lffsyfavhf isnswlmwli inlvqmapis
     1561 amvrmyiffa sfyyvwksyv hvvdgcnsst cmmcykrnra trvecttivn gvrrsfyvya
     1621 nggkgfcklh nwncvncdtf cagstfisde vardlslqfk rpinptdqss yivdsvtvkn
     1681 gsihlyfdka gqktyerhsl shfvnldnlr anntkgslpi nvivfdgksk ceessaksas
     1741 vyysqlmcqp illldqalvs dvgdsaevav kmfdayvntf sstfnvpmek lktlvataea
     1801 elaknvsldn vlstfisaar qgfvdsdvet kdvveclkls hqsdievtgd scnnymltyn
     1861 kvenmtprdl gacidcsarh inaqvakshn ialiwnvkdf mslseqlrkq irsaakknnl
     1921 pfkltcattr qvvnvvttki alkgg
//

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