ORF3a, COVID-19. Proteiini 3a muodostaa jonikanavan viroporiini (Proteiini 3a on 275 aminohappoa)

https://www.ncbi.nlm.nih.gov/gene/43740569
https://www.ncbi.nlm.nih.gov/protein/YP_009724391.1

LOCUS       YP_009724391             275 aa            linear   VRL 28-JAN-2020
DEFINITION  ORF3a protein [Severe acute respiratory syndrome coronavirus 2].
ACCESSION   YP_009724391
VERSION     YP_009724391.1
DBLINK      BioProject: PRJNA485481
DBSOURCE    REFSEQ: accession NC_045512.2
KEYWORDS    RefSeq.
SOURCE      Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
  ORGANISM  Severe acute respiratory syndrome coronavirus 2
            Viruses; Riboviria; Nidovirales; Cornidovirineae; Coronaviridae;
            Orthocoronavirinae; Betacoronavirus; Sarbecovirus.
REFERENCE   1  (residues 1 to 275)
  AUTHORS   Wu,F., Zhao,S., Yu,B., Chen,Y.-M., Wang,W., Hu,Y., Song,Z.-G.,
            Tao,Z.-W., Tian,J.-H., Pei,Y.-Y., Yuan,M.L., Zhang,Y.-L.,
            Dai,F.-H., Liu,Y., Wang,Q.-M., Zheng,J.-J., Xu,L., Holmes,E.C. and
            Zhang,Y.-Z.
  TITLE     A novel coronavirus associated with a respiratory disease in Wuhan
            of Hubei province, China
  JOURNAL   Unpublished
REFERENCE   2  (residues 1 to 275)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-JAN-2020) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 275)
  AUTHORS   Wu,F., Zhao,S., Yu,B., Chen,Y.-M., Wang,W., Hu,Y., Song,Z.-G.,
            Tao,Z.-W., Tian,J.-H., Pei,Y.-Y., Yuan,M.L., Zhang,Y.-L.,
            Dai,F.-H., Liu,Y., Wang,Q.-M., Zheng,J.-J., Xu,L., Holmes,E.C. and
            Zhang,Y.-Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JAN-2020) Shanghai Public Health Clinical Center &
            School of Public Health, Fudan University, Shanghai, China
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to QHD43417.
            Annotation was added using homology to SARSr-CoV NC_004718.3. If
            you have questions or suggestions, please email us at
            info@ncbi.nlm.nih.gov and include the accession number
            NC_045512.##Find all other Wuhan seafood market pneumonia virus
            (2019-nCov) sequences at
            https://www.ncbi.nlm.nih.gov/genbank/2019-ncov-seqs/
            
            ##Assembly-Data-START##
            Assembly Method       :: Megahit v. V1.1.3
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            COMPLETENESS: full length.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Severe acute respiratory syndrome coronavirus
                     2"
                     /isolate="Wuhan-Hu-1"
                     /host="Homo sapiens"
                     /db_xref="taxon:2697049"
                     /country="China"
                     /collection_date="Dec-2019"
     Protein         1..275
                     /product="ORF3a protein"
                     /calculated_mol_wt=30992
     CDS             1..275
                     /gene="ORF3a"
                     /locus_tag="GU280_gp03"
                     /coded_by="NC_045512.2:25393..26220"
                     /db_xref="GeneID:43740569"
ORIGIN      
        1 mdlfmrifti gtvtlkqgei kdatpsdfvr atatipiqas lpfgwlivgv allavfqsas
       61 kiitlkkrwq lalskgvhfv cnllllfvtv yshlllvaag leapflylya lvyflqsinf
      121 vriimrlwlc wkcrsknpll ydanyflcwh tncydycipy nsvtssivit sgdgttspis
      181 ehdyqiggyt ekwesgvkdc vvlhsyftsd yyqlystqls tdtgvehvtf fiynkivdep
      241 eehvqihtid gssgvvnpvm epiydepttt tsvpl
//