SARS-2 ORF9 N-proteiinin interaktioprofiilista Ainakin 15 ihmisen proteiinia on interaktioproteiineja

https://covid-19.uniprot.org/uniprotkb/P0DTC9

Interaction

subunit

Homooligomer. Both monomeric and oligomeric forms interact with RNA. Interacts with protein M. Interacts with protein E. May bind to host HNRNPA1. Interacts with NSP3; this interaction serves to tether the genome to the newly translated replicase-transcriptase complex at a very early stage of infection (By similarity). May interact with host SMAD3 (By similarity)

Protein-protein interaction databases

ComplexPortal

• CPX-5686

• SARS-CoV-2 nucleocapsid complex

IntAct

• P0DTC9

15 interactors

		Names	Type	Interactions	Links		Accession	Description
	1	g3bp2_human	protein	1	EBI-1044298		EBI-1044298	Ras GTPase-activating protein-binding protein 2
	2	g3bp1_human	protein	1	EBI-1047359		EBI-1047359	Ras GTPase-activating protein-binding protein 1
	3	larp1_human	protein	1	EBI-1052114		EBI-1052114	La-related protein 1
	4	mov10_human	protein	1	EBI-1055820		EBI-1055820	Helicase MOV-10
	5	rl36_human	protein	1	EBI-1057689		EBI-1057689	60S ribosomal protein L36
	6	fa98a_human	protein	1	EBI-1210765		EBI-1210765	Protein FAM98A
	7	u3ip2_human	protein	1	EBI-2115327		EBI-2115327	U3 small nucleolar RNA-interacting protein 2
	8	n_wcpv	protein	15	EBI-25475856		EBI-25475856	Nucleoprotein
	9	rbm28_human	protein	1	EBI-2878099		EBI-2878099	RNA-binding protein 28
	10	csk22_human	protein	1	EBI-347451		EBI-347451	Casein kinase II subunit alpha'
	11	csk2b_human	protein	1	EBI-348169		EBI-348169	Casein kinase II subunit beta
	12	ddx21_human	protein	1	EBI-357942		EBI-357942	Nucleolar RNA helicase 2
	13	pabp4_human	protein	1	EBI-372844		EBI-372844	Polyadenylate-binding protein 4
	14	rent1_human	protein	1	EBI-373471		EBI-373471	Regulator of nonsense transcripts 1
	15	snip1_human	protein	1	EBI-749336		EBI-749336	Smad nuclear-interacting protein 1
	16	pabp1_human	protein	1	EBI-81531		EBI-81531	Polyadenylate-binding protein 1