TBCA, (5q14.1). Tubulin-specific chaperone A.
https://www.genecards.org/cgi-bin/carddisp.pl?gene=TBCA&keywords=TBCA
The product of this gene is one of four proteins
(cofactors A, D, E, and C) involved in the pathway leading to correctly
folded beta-tubulin from folding intermediates. Cofactors A and D are
believed to play a role in capturing and stabilizing beta-tubulin
intermediates in a quasi-native confirmation. Cofactor E binds to the
cofactor D/beta-tubulin complex; interaction with cofactor C then causes
the release of beta-tubulin polypeptides that are committed to the
native state. This gene encodes chaperonin cofactor A. Multiple
alternatively spliced transcript variants encoding different isoforms
have been found for this gene. [provided by RefSeq, Jul 2014]
https://iiif.elifesciences.org/lax:08811%2Felife-08811-fig1-v2.tif/full/1500,/0/default.jpg
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