PMIS (lasten monisysteeminen tulehdusoireyhtymä), MIS-C (monisysteeminen tulehdusoireyhtymä lapsilla)

https://www.aljazeera.com/indepth/features/doctors-race-understand-illness-afflicting-children-200519063453208.html

Doctors race to understand new illness afflicting children

More and more cases of a Kawasaki-like disease, called PMIS or MIS-C, reported among children exposed to coronavirus.

Multisystem inflammatory syndrome 

The Zoom call was the first to put clinicians from both sides of the Atlantic Ocean in the same virtual room as their colleagues from Boston, London, Barcelona, Genoa and Geneva. There were 1,800 viewers on the call; the conference was so full that some used FaceTime to screen-share Zoom.
Doctors in cities that had just surfaced from the full force of a COVID-19 outbreak addressed doctors in cities that were at the peak of the wave.
They named the new illness paediatric multisystem inflammatory syndrome (PMIS) or multisystem inflammatory syndrome in children (MIS-C) - the name is still evolving - described its symptoms, and prescribed a course of treatment. Each case would require a team of specialists and the facilities of a well-resourced city-based children's hospital.
"We should know in a couple of weeks how wide the spectrum is. We've literally been hearing about cases every day, but we're not gathering systematic data. It's all word of mouth from Zoom conferences and webinars," Dr Levin said on May 12, writing a few days later to say that data-collection processes had already improved.

Signs of PMIS/MIS-C

The National Health Service in the UK, American CDC, and WHO have alerted doctors to look for the following signs in children presenting to hospitals:

Body temperature

Persistent fever lasting 24 hours or up to 3-days

Organs

Dysfunction of one or more organs, primarily the heart, but also kidneys, lungs, skin, and neurological system

Symptoms

Two of the following: rashes; conjunctivitis; inflammation in mouth, hands or feet; hypo-tension (low blood pressure); acute gastrointestinal problems; coagulopathy (blood unable to clot properly)

Coronavirus link

Positive or negative test for SARS-CoV-2 virus; positive test for SARS-CoV-2 antibodies; or likely contact with COVID-19 patients

Age range

Children can be under 19 or 21 years old

Source: World Health Organization, Centers for Disease Control and Prevention, Royal College of Paediatrics and Child Health

 Vertaa aiemmin tunnettuun Kawsasakin oireyhtymään:

Kawasaki disease

Kawasaki disease, named after the doctor who examined its symptoms in the 1960s in Japan, is a rare illness that mostly affects children below the age of five. Patients develop a high persistent fever, conjunctivitis and rashes. Their tongue, throat and lips redden, and their hands and feet often swell, with redness in the palms and soles. Some children develop an enlarged lymph node on one side of the neck.
The illness can lead to a coronary artery aneurysm, which is a swelling in the vessel that oxygenates the heart muscle. Kawasaki disease is reported in all races, but Asian children have the highest incidence of illness, suggesting a possible genetic susceptibility. Though frightening for parents and considered serious by physicians, most children do well with aggressive early treatment.
Dr D'Antiga and his team opened their clinical records to recall all incoming cases of Kawasaki disease over the last five years, and compared these to those recorded since COVID-19 hit Bergamo.
The 10 patients they had seen (all of whom were from the region) represented a 30-fold increase in episodes per month. But the new patients were older than the typical Kawasaki patient - one was two, others were between five and nine years old, one was 16 - and their conditions were more severe.