SARS-2 ORF5 Membrane protein (M) - interaktioprofiilista (30 ihmisen proteiinia)

P0DTC5 · VME1_SARS2
(222 residues)

Membrane Protein (M protein): Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
Only remote homologues were identified as potential template structures, limiting the expected quality of the models.
See here for available low quality models.

Interaction

subunit

Homomultimer. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in RNA packaging into the virus (By similarity). Interacts with the accessory proteins 3a and 7a (By similarity)

Protein-protein interaction databases

IntAct

• P0DTC5

30 interactors

p12pp
		Names	Type	Interactions	Links		Accession	Description
Names Type Interactions Links Accession Description pp12pp 21 acadm_human protein 1 EBI-514381 EBI-514381 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial 22 int4_human protein 1 EBI-5663129 EBI-5663129 Integrator complex subunit 4 23 odc_human protein 1 EBI-6268670 EBI-6268670 Mitochondrial 2-oxodicarboxylate carrier 24 fa8a1_human protein 1 EBI-6309101 EBI-6309101 Protein FAM8A1 25 at1b1_human protein 1 EBI-714630 EBI-714630 Sodium/potassium-transporting ATPase subunit beta-1 26 rtn4_human protein 1 EBI-715945 EBI-715945 Reticulon-4 27 saal1_human protein 1 EBI-721193 EBI-721193 Protein SAAL1 28 mppb_human protein 1 EBI-721199 EBI-721199 Mitochondrial-processing peptidase subunit beta 29 fakd5_human protein 1 EBI-747570 EBI-747570 FAST kinase domain-containing protein 5, mitochondrial 30 aar2_human protein 1 EBI-748721 EBI-748721 Protein AAR2 homolog 31 reep6_human protein 1 EBI-750345 EBI-750345 Receptor expression-enhancing protein 6
	1	znt7_human	protein	1	EBI-1043569		EBI-1043569	Zinc transporter 7
	2	sytm_human	protein	1	EBI-1045099		EBI-1045099	Threonine--tRNA ligase, mitochondrial
	3	gcp3_human	protein	1	EBI-1046278		EBI-1046278	Gamma-tubulin complex component 3
	4	bzw2_human	protein	1	EBI-1051021		EBI-1051021	Basic leucine zipper and W2 domain-containing protein 2
	5	etfa_human	protein	1	EBI-1052886		EBI-1052886	Electron transfer flavoprotein subunit alpha, mitochondrial
	6	vata_human	protein	1	EBI-1054757		EBI-1054757	V-type proton ATPase catalytic subunit A
	7	vkgc_human	protein	1	EBI-10963113		EBI-10963113	Vitamin K-dependent gamma-carboxylase
	8	stom_human	protein	1	EBI-1211440		EBI-1211440	Erythrocyte band 7 integral membrane protein
	9	aass_human	protein	1	EBI-1237169		EBI-1237169	Alpha-aminoadipic semialdehyde synthase, mitochondrial
	10	reep5_human	protein	1	EBI-1549827		EBI-1549827	Receptor expression-enhancing protein 5
	11	prep_human	protein	1	EBI-2432778		EBI-2432778	Presequence protease, mitochondrial
	12	mppa_human	protein	1	EBI-2514696		EBI-2514696	Mitochondrial-processing peptidase subunit alpha
	13	m_wcpv	protein	30	EBI-25475853		EBI-25475853	Membrane protein
	14	yif1a_human	protein	1	EBI-2799703		EBI-2799703	Protein YIF1A
	15	znt9_human	protein	1	EBI-2818242		EBI-2818242	Zinc transporter 9
	16	ano6_human	protein	1	EBI-2820640		EBI-2820640	Anoctamin-6
	17	akp8l_human	protein	1	EBI-357530		EBI-357530	A-kinase anchor protein 8-like
	18	gcp2_human	protein	1	EBI-357881		EBI-357881	Gamma-tubulin complex component 2
	19	psmd8_human	protein	1	EBI-359304		EBI-359304	26S proteasome non-ATPase regulatory subunit 8
	20	coq8b_human	protein	1	EBI-3957978		EBI-3957978	Atypical kinase COQ8B, mitochondrial