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fredag 22 april 2022

Pari päivää sitten merkattu uudeksi asia #541 eräässä BA.2* variantissa ilmennyt Spikemutaatio : K417T. Linjaa selvitellään.

 

BA.2 (+ C25416T) lineage with S:K417T common in India [>5%] and growing in UK [140 seq] #541

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corneliusroemer opened this issue 13 days ago · 2 comments 
Ennestään tunentaan K417T  spike-mutaatio gammavariantista P.1. 

(Cornelius sanoo):

It's plausible that BA.2 + S:K417T has a growth advantage. So I went and checked out all the global lineages. There are multiple, which again points to growth advantage.

This is a lineage that appears smaller than the UK one #528, but in fact I think it's bigger because it makes up 2% in India - which has many more cases than UK for sure. It also looks like there's been import into UK from India. There are now 100 sequences from UK.

I think it's definitely worth designating this one.

I checked whether it's clean. It is, it lies on the big BA.2 branch with C25416T (chrisruis- nijmimerkki)  you remember I wanted to give this one a label, but unfortunately it's synonymous). Anyways, this will help show that C25416T is a big branch. The other lineage on it is #499 (BA.2.12(.1)).

 

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