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fredag 8 april 2022

Omicronlinja BA.2 on saanut vähitellen alaryhmiä, nyt jo BA.2.12 on merkattuna.

On havaittu, että BA.2 linjaan on ilmentynyt  alainja, josa esiintyy Spike mutaatio  S704L. Lisäksi tämä linja on saanut alalinjan, jossa esiintyy L452Q, jolla sinänsä on jo ennenstään paha maine. Myös BA.1 linjassa on havaittu vastaavaa alalinjojen muodostumsita.

Proposal for a Potential BA.2.x with Spike S704L (2.2k Seqs), and Its Potential sublineage with Additional Spike L452Q (240 Seqs) #499 

 

BA.2 alaryhmäluettelo  kahden uuden linjan erottamisen jälkeen  

Ensinnäkin päivän VOC-lista: Huomaa , että siinä on merkittynä uudet mutaatiot, joita esiintyy BA.4 ja BA.5 linjoissa : L452R ja  F486V. niitä ei ole BA.1 ja BA.3 linjoissa ja  eikä kaiketi  enää jäljellä BA.2 linjoissa, josita  BA,4 ja BA.5 on siirretty erikseen.  Katson alle vain mitä nyt on BA.2 linjoisa jäljellä tänään  13.4. 2022.

 

Currently circulating variants of concern (VOCs):

WHO label 

Pango  
lineage
GISAID cladeNextstrain clade Additional amino acid changes monitored°Earliest documented  
samples 
Date of designation 
Delta 

B.1.617.2

G/478K.V121A, 21I, 21J

+S:K417N

+S:E484K

India,  
Oct-2020 
VOI: 4-Apr-2021 
VOC: 11-May-2021
Omicron*B.1.1.529GR/484A

21K, 21L, 21M

 

+S:R346K

+S:L452R

+S:F486V

Multiple countries, Nov-2021

VUM: 24-Nov-2021

VOC: 26-Nov-2021

 

* Includes BA.1, BA.2, BA.3, BA.4, BA.5 and descendent lineages. It also includes BA.1/BA.2 circulating recombinant forms such as XE. WHO emphasizes that these descendant lineages should be monitored as distinct lineages by public health authorities and comparative assessments of their virus characteristics should be undertaken.

The full list of Pango lineages can be found here: https://cov-lineages.org/lineage_list.html; for FAQ, visit: https://www.pango.network/faqs/

° Only found in a subset of sequences

BA.2 ja sen alalinjat tänään 13.4. 2022:  (Ilman rekombinaatioita X tässä yhteydessä, jotka ovat vasta näiden jälkeen)

 https://cov-spectrum.org/explore/World/AllSamples/Past6M/variants?nucMutations=22792T%2C22916A%2C23767G&pangoLineage=BA.2*&aaMutations1=ORF3a%3A78Y&nucMutations1=A1230G%2CT3610C%2CT4111C%2CC15342T%2CC20178T%2CA24433G%2CC28472T%2CG29508T&pangoLineage1=BA.2*&
 
BA.2 United Kingdom 47.0%, Denmark 21.0%, Germany 9.0%, United States of America 3.0%, Sweden 3.0%2021-11-0917635193Alias of B.1.1.529.2, from pango-designation issue #361Omicron
BA.2.1 United Kingdom 59.0%, Sweden 26.0%, India 5.0%, Denmark 2.0%, Germany 2.0% 2021-12-20 532 15912 Alias of B.1.1.529.2.1, UK lineage
BA.2.2 Hong_Kong 63.0%, United Kingdom 20.0%, Australia 6.0%, United States of America 2.0%, Poland 1.0% 2021-12-29 68 1311 Alias of B.1.1.529.2.2, Hong Kong lineage
BA.2.3 United Kingdom 24.0%, India 16.0%, Germany 14.0%, United States of America 9.0%, Denmark 7.0% 2021-09-29 1938 98062 Alias of B.1.1.529.2.3, lineage in Philippines and other countries
BA.2.3.1

59 0 Alias of B.1.1.529.2.3.1, Japan lineage, from pango-designation issue #495
BA.2.3.2

118 0 Alias of B.1.1.529.2.3.2, Vietnam and Japan lineage
BA.2.4

96 0 Alias of B.1.1.529.2.4, Singapore lineage
BA.2.5

387 0 Alias of B.1.1.529.2.5, lineage in Portugal and other countries
BA.2.6

127 0 Alias of B.1.1.529.2.6, lineage in France and other countries
BA.2.7

519 0 Alias of B.1.1.529.2.7, USA lineage
BA.2.8

1614 0 Alias of B.1.1.529.2.8, UK lineage, from pango-designation issue #486
BA.2.9

4815 0 Alias of B.1.1.529.2.9, European lineage, from pango-designation issue #432
BA.2.9.1

99 0 Alias of B.1.1.529.2.9.1, UK lineage, from pango-designation issue #530
BA.2.10

11899 0 Alias of B.1.1.529.2.10, lineage from pango-designation issue #496
BA.2.10.1

1669 0 Alias of B.1.1.529.2.10.1, lineage in Singapore and other countries
BA.2.11

27 0 Alias of B.1.1.529.2.11, France lineage, from pango-designation issue #491
BA.2.12

1495 0 Alias of B.1.1.529.2.12, North America and Europe lineage, from pango-designation issue #499
BA.2.12.1

265 0 Alias of B.1.1.529.2.12.1, USA and Canada lineage, from pango-designation issue #499
BA.2.13

530Alias of B.1.1.529.2.13, Europe lineage, from pango-designation issue #531  

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