Theofylliini ja riboswitch

https://academic.oup.com/nar/article/44/18/9005/2468359https://academic.oup.com/nar/article/44/18/9005/2468359

Theophylline, also known as 1,3-dimethylxanthine, is a methylxanthine drug used in therapy for respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma under a variety of brand names. As a member of the xanthine family, it bears structural and pharmacological similarity to theobromine and caffeine, and is readily found in nature, being present in tea (Camellia sinensis) and cocoa (Theobroma cacao). A small amount of theophylline is one of the products of caffeine metabolic processing in the liver.<sup>[1]

https://en.wikipedia.org/wiki/Theophylline</sup>

Original Article | Open Access

Volume 2 |Article ID 607278 | 7 pages | https://doi.org/10.1093/ecam/neh081

Inhibition of SARS-CoV 3C-like Protease Activity by Theaflavin-3,3'-digallate (TF3)

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Chia-Nan Chen,¹ Coney P. C. Lin,¹ Kuo-Kuei Huang,¹ Wei-Cheng Chen,¹ Hsin-Pang Hsieh,¹ Po-Huang Liang,² and John T.-A. Hsu^1,3

¹Division of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Taipei, Taiwan
²Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan
³Department of Chemical Engineering, National Tsing Hua University, Hsinchu, Taiwan