SARS2 Spike proteiini

surface glycoprotein [Severe acute respiratory syndrome coronavirus 2]

NCBI Reference Sequence: YP_009724390.1

Identical Proteins FASTA Graphics

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LOCUS       YP_009724390            1273 aa            linear   VRL 30-MAR-2020
DEFINITION  surface glycoprotein [Severe acute respiratory syndrome coronavirus
            2].
ACCESSION   YP_009724390
VERSION     YP_009724390.1
DBLINK      BioProject: PRJNA485481
DBSOURCE    REFSEQ: accession NC_045512.2
KEYWORDS    RefSeq.
SOURCE      Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
  ORGANISM  Severe acute respiratory syndrome coronavirus 2
            Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
            Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae;
            Betacoronavirus; Sarbecovirus.
REFERENCE   1  (residues 1 to 1273)
  AUTHORS   Wu,F., Zhao,S., Yu,B., Chen,Y.-M., Wang,W., Hu,Y., Song,Z.-G.,
            Tao,Z.-W., Tian,J.-H., Pei,Y.-Y., Yuan,M.L., Zhang,Y.-L.,
            Dai,F.-H., Liu,Y., Wang,Q.-M., Zheng,J.-J., Xu,L., Holmes,E.C. and
            Zhang,Y.-Z.
  TITLE     A novel coronavirus associated with a respiratory disease in Wuhan
            of Hubei province, China
  JOURNAL   Unpublished
REFERENCE   2  (residues 1 to 1273)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-JAN-2020) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 1273)
  AUTHORS   Wu,F., Zhao,S., Yu,B., Chen,Y.-M., Wang,W., Hu,Y., Song,Z.-G.,
            Tao,Z.-W., Tian,J.-H., Pei,Y.-Y., Yuan,M.L., Zhang,Y.-L.,
            Dai,F.-H., Liu,Y., Wang,Q.-M., Zheng,J.-J., Xu,L., Holmes,E.C. and
            Zhang,Y.-Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JAN-2020) Shanghai Public Health Clinical Center &
            School of Public Health, Fudan University, Shanghai, China
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to QHD43416.
            Annotation was added using homology to SARSr-CoV NC_004718.3. ###
            Formerly called 'Wuhan seafood market pneumonia virus.' If you have
            questions or suggestions, please email us at info@ncbi.nlm.nih.gov
            and include the accession number NC_045512.### Protein structures
            can be found at
            https://www.ncbi.nlm.nih.gov/structure/?term=sars-cov-2.### Find
            all other Severe acute respiratory syndrome coronavirus 2
            (SARS-CoV-2) sequences at
            https://www.ncbi.nlm.nih.gov/genbank/sars-cov-2-seqs/
            
            ##Assembly-Data-START##
            Assembly Method       :: Megahit v. V1.1.3
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            COMPLETENESS: full length.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..1273
                     /organism="Severe acute respiratory syndrome coronavirus
                     2"
                     /isolate="Wuhan-Hu-1"
                     /host="Homo sapiens"
                     /db_xref="taxon:2697049"
                     /country="China"
                     /collection_date="Dec-2019"
     Protein         1..1273
                     /product="surface glycoprotein"
                     /calculated_mol_wt=141048
     Region          330..583
                     /region_name="Spike_rec_bind"
                     /note="Spike receptor binding domain; pfam09408"
                     /db_xref="CDD:370471
 This domain corresponds is the immunogenic receptor binding 
domain of the protein which binds to angiotensin-converting enzyme 2 
(ACE2).
     Region          662..1270
                     /region_name="Corona_S2"
                     /note="Coronavirus S2 glycoprotein; pfam01601"
                     /db_xref="CDD:279881"
     CDS             1..1273
                     /gene="S"
                     /locus_tag="GU280_gp02"
                     /gene_synonym="spike glycoprotein"
                     /coded_by="NC_045512.2:21563..25384"
                     /note="structural protein; spike protein"
                     /db_xref="GeneID:43740568"
ORIGIN      
        1 mfvflvllpl vssqcvnltt rtqlppaytn sftrgvyypd kvfrssvlhs tqdlflpffs
       61 nvtwfhaihv sgtngtkrfd npvlpfndgv yfasteksni irgwifgttl dsktqslliv
      121 nnatnvvikv cefqfcndpf lgvyyhknnk swmesefrvy ssannctfey vsqpflmdle
      181 gkqgnfknlr efvfknidgy fkiyskhtpi nlvrdlpqgf saleplvdlp iginitrfqt
      241 llalhrsylt pgdsssgwta gaaayyvgyl qprtfllkyn engtitdavd caldplsetk
      301 ctlksftvek giyqtsnfrv qptesivrfp nitnlcpfge vfnatrfasv yawnrkrisn
      361 cvadysvlyn sasfstfkcy gvsptklndl cftnvyadsf virgdevrqi apgqtgkiad
      421 ynyklpddft gcviawnsnn ldskvggnyn ylyrlfrksn lkpferdist eiyqagstpc
      481 ngvegfncyf plqsygfqpt ngvgyqpyrv vvlsfellha patvcgpkks tnlvknkcvn
      541 fnfngltgtg vltesnkkfl pfqqfgrdia dttdavrdpq tleilditpc sfggvsvitp
      601 gtntsnqvav lyqdvnctev pvaihadqlt ptwrvystgs nvfqtragcl igaehvnnsy
      661 ecdipigagi casyqtqtns prrarsvasq siiaytmslg aensvaysnn siaiptnfti
      721 svtteilpvs mtktsvdctm yicgdstecs nlllqygsfc tqlnraltgi aveqdkntqe
      781 vfaqvkqiyk tppikdfggf nfsqilpdps kpskrsfied llfnkvtlad agfikqygdc
      841 lgdiaardli caqkfngltv lpplltdemi aqytsallag titsgwtfga gaalqipfam
      901 qmayrfngig vtqnvlyenq klianqfnsa igkiqdslss tasalgklqd vvnqnaqaln
      961 tlvkqlssnf gaissvlndi lsrldkveae vqidrlitgr lqslqtyvtq qliraaeira
     1021 sanlaatkms ecvlgqskrv dfcgkgyhlm sfpqsaphgv vflhvtyvpa qeknfttapa
     1081 ichdgkahfp regvfvsngt hwfvtqrnfy epqiittdnt fvsgncdvvi givnntvydp
     1141 lqpeldsfke eldkyfknht spdvdlgdis ginasvvniq keidrlneva knlneslidl
     1201 qelgkyeqyi kwpwyiwlgf iagliaivmv timlccmtsc csclkgccsc gscckfdedd
     1261 sepvlkgvkl hyt
//