Miltähän kehoproteiinijärjestelmältä EBOV on pihistänyt tuollaisen organisatorisen kyvyn?- aikamme einsteinit selvittävät tätä asiaa parhaillaan.
The Organisation of Ebola Virus Reveals a Capacity for Extensive, Modular Polyploidy
The Organisation of Ebola Virus Reveals a Capacity for Extensive, Modular Polyploidy
http://openi.nlm.nih.gov/detailedresult.php?img=3256159_pone.0029608.g006&req=4
pone-0029608-g006: Schematic model of Ebola virus genome packaging.EBOV appears pleomorphic, but an underlying structural organization is maintained. In the model we show the three basic morphological forms of EBOV particles; empty, linked, and continuous.
Single genome (G1) virus and multi-genome particles are shown budding from the cell.
In this model genomes are assembled in the host cell and transported to the surface where the end-to-end apposition that we have observed by cryo-EM in mature virions takes place during (or prior to) budding and envelopment at the plasma membrane. The color-coding is as follows: nucleocapsids, red, yellow and orange helices; nucleocapsid protein, purple spheres; VP40, green ovals, VP24/VP35 bridges, blue oval; GP spikes, red; microtubules, brown.
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