https://www.ecdc.europa.eu/en/covid-19/variants-concern
Variants of Interest (VOI)
For these variants, evidence is available on genomic properties, epidemiological evidence or in-vitro evidence that could imply a significant impact on transmissibility, severity and/or immunity, realistically having an impact on the epidemiological situation in the EU/EEA. However, the evidence is still preliminary or is associated with major uncertainty. In addition, all the criteria for variants under monitoring outlined below apply.
WHO label |
Lineage + additional mutations |
Country first detected (community) |
Spike mutations of interest |
Year and month first detected |
Impact on transmissibility |
Impact on immunity |
Impact on severity |
Transmission in EU/EEA |
|---|---|---|---|---|---|---|---|---|
Omicron |
BA.2 + L452X (x) |
n/a |
L452X |
n/a |
No evidence |
Increased (7) |
No evidence |
Detected (a) |
Omicron |
India |
(y) |
May 2022 |
No evidence |
Increased (9, 10) |
No evidence |
Detected (a) |
x: Any amino-acid substitution
y: W152R, F157L, I210V, G257S, D339H, G446S, N460K, Q493 (reversion)
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