ECDC: Sars-CoV-2 : Variants of Concern (VOC) 8.9.2022

https://www.ecdc.europa.eu/en/covid-19/variants-concern

Variants of Concern (VOC)

For these variants, clear evidence is available indicating a significant impact on transmissibility, severity and/or immunity that is likely to have an impact on the epidemiological situation in the EU/EEA. The combined genomic, epidemiological, and in-vitro evidence for these properties invokes at least moderate confidence. In addition, all the criteria for variants of interest and under monitoring outlined below apply.

WHO label	Lineage + additional mutations	Country first detected (community)	Spike mutations of interest	Year and month first detected	Impact on transmissibility	Impact on immunity	Impact on severity	Transmission in EU/EEA
Omicron	BA.2	South Africa	(y)	November 2021	Increased (v) (1, 2)	Increased (v) (3)	Reduced (v) (4, 5)	Community
Omicron	BA.4	South Africa	L452R, F486V, R493Q	January 2022	No evidence	Increased (6, 7)	No evidence	Community
Omicron	BA.5	South Africa	L452R, F486V, R493Q	February 2022	No evidence	Increased (6, 7)	Unclear (8)	Dominant

 

y: G142D, N211I, Δ212, V213G, G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K

All sub-lineages of the listed lineages are also included in the variant, e.g., BA.1.1 is included in Omicron BA.1 as it is a sub-lineage of BA.1.