https://www.ecdc.europa.eu/en/covid-19/variants-concern
SARS-CoV-2 variants of concern (VOC) as of 8 September 2022
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ECDC regularly assesses new evidence on variants detected through epidemic intelligence, rules-based genomic variant screening, or other scientific sources. If a decision is made to add, remove, or change the category for any variant, the tables are updated to reflect this change. The tables are regularly sent for consultation to ECDC and WHO Regional Office for Europe’s joint virus characterisation working group. The rules-based genomic screening is performed using an open source algorithm
. The weekly ECDC variant surveillance data report can be found in the weekly COVID-19 country overviews published on ECDC’s website.
More information on variants is available on
Description of the tables
The tables include:
Category: variant of concern (VOC), variant of interest (VOI), or variant under monitoring (VUM) (see definition above each table). Note that it is a possible for a VOC, VOI or VUM to also be a part of a broader VOC, VOI, or VUM definition, e.g. B.1.617.2+E484X is also a part of B.1.617.2, this means that there is enough evidence to fulfil the VOC, VOI or VUM criteria for this variant using the broader variant as a reference.
WHO label: As of 31st May 2021, WHO proposed labels for global SARS-CoV-2 variants of concern and variants of interest
to be used alongside the scientific nomenclature in communications about variants to the public. This list includes variants on WHO’s global list of VOC and VOI, and is updated as WHO’s list changes.
Lineage and additional mutations: the variant designation specified by one or more Pango lineages and any additional characteristic spike protein changes. An alternate description may be used if the variant is not easy to describe using this nomenclature. For updated information on Pango lineages and definition of lineages and for instructions on how to suggest new lineages, visit the Pango lineages website
. Each lineage in then table is linked to the respective lineage page on the Pango lineages website.
Country first detected: only present if there is moderate confidence in the evidence relating to the first country of detection.
Spike mutations of interest: not all spike protein amino acid changes are included – this is not a full reference for assignment of the variants. It includes changes to spike protein residues 319-541 (receptor binding domain) and 613-705 (the S1 part of the S1/S2 junction and a small stretch on the S2 side), and any additional unusual changes specific to the variant.
Year and month first detected: as reported in the GISAID EpiCoV database. This can be adjusted backwards in time if new retrospective detections are made.
Evidence concerning properties in three different categories:
Transmissibility
Immunity
Infection severity
Each category is annotated as increased, reduced, similar, unclear, or no evidence depending on the currently available evidence. Increased or reduced means that there is evidence demonstrating that the property is different enough for the variant compared to previously circulating variants that it is likely to have an impact on the epidemiological situation in the EU/EEA. Similar means that there is evidence that demonstrates that the property is not different enough for this variant compared to previously circulating variants that it is unlikely to have an impact. Unclear means that the current evidence is preliminary or contradictory enough to make the assessment uncertain. No evidence means that no evidence has yet been evaluated for this category. The evidence is further annotated with v or m to indicate whether the evidence is available for the variant itself (v) or for mutations associated with the variant (m).
Transmission in the EU/EEA: categorised as dominant, community, outbreak(s), and sporadic/travel. The categories are qualitative, and the assessment is based on surveillance data collected in TESSy, GISAID EpiCoV data, epidemic intelligence data, and direct communications with the affected countries.
(Asetan eri otsikoiden alle VOCvarianttilinjat VOI ja VUM-varianttilinjat ja de-eskaloidut. Ne katoamassa olevat ovat pitkä luettelo joten annan niistä vain linkkitiedon).ja historiikkia.
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