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torsdag 25 maj 2023

PubMed Haku: Dominant HIV-1 virus 2023 18 artikkelia

 https://pubmed.ncbi.nlm.nih.gov/?term=Dominant+HIV-1+viruses+2023

18  answers

 Ensimmäinen lähde kuvaa immuunivajewita, joissa viimeisenä mainitaan sekundäärinen immuunivaje, joka aiheutuu HIV-infektiosta: . 

Immunodeficiency. Justiz Vaillant AA, Qurie A. 2022 Jul 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 29763203 Free Books & Documents. Acquired Immune Deficiency Syndrome (AIDS): Caused by the human immunodeficiency virus (HIV), which is a retrovirus transmitted sexually, perinatally, or blood products. ...Interleukin-2 and other cytokines are decreased. Infected cells may be killed by HIV- …

Characterization of Megabat-Favored, CA-Dependent Susceptibility to Retrovirus Infection.
Ohkura S, Horie M, Shimizu M, Nakagawa S, Osanai H, Miyagawa Y, Morita R. J Virol. 2023 Mar 30;97(3):e0180322. doi: 10.1128/jvi.01803-22. Epub 2023 Feb 13. PMID: 36779757
To answer this, we studied the susceptibility of 12 cell lines from 11 bat species to four well-studied retroviruses (human and simian immunodeficiency viruses [HIV and SIV] and murine leukemia viruses [B- and N-MLV]). ...Therefore, HIV-1 suscep … 
 
HIV-1 reservoir evolution in infants infected with clade C from Mozambique.
Koofhethile CK, Rinaldi S, Rassadkina Y, Dinh VB, Gao C, Pallikkuth S, Garcia-Broncano P, de Armas LR, Pahwa R, Cotugno N, Vaz P, Lain MG, Palma P, Yu XG, Shapiro R, Pahwa S, Lichterfeld M. Int J Infect Dis. 2023 Feb;127:129-136. doi: 10.1016/j.ijid.2022.11.042. Epub 2022 Dec 5. PMID: 36476348 Free PMC article.
RESULTS: We observed a rapid decline in the frequency of intact proviruses, leading to a disproportional under-representation of intact HIV-1 sequences within the total number of HIV-1 DNA sequences after 12-24 months of therapy. ...CONCLUSION: Togethe …
 
Prevalence of HIV Transmitted Drug Resistance in Nanjing from 2018 to 2021.
Su Y, Qi M, Zhong M, Yu N, Chen C, Ye Z, Cheng C, Hu Z, Zhang H, Wei H. Infect Drug Resist. 2023 Feb 2;16:735-745. doi: 10.2147/IDR.S391296. eCollection 2023. PMID: 36756611 Free PMC article.
Therefore, this study aimed to investigate the epidemic characteristics of and risk factors for human immunodeficiency virus (HIV)-1 TDR in Nanjing from 2018 to 2021 to provide support for clinical management. METHODS: The HIV-1 Pol gene was amp …
 
CD3+CD56+ and CD3-CD56+ lymphocytes in the cerebrospinal fluid of persons with HIV-1 subtypes B and C.
de Almeida SM, Beltrame MP, Tang B, Rotta I, Justus JLP, Schluga Y, da Rocha MT, Martins E, Liao A, Abramson I, Vaida F, Schrier R, Ellis RJ. J Neuroimmunol. 2023 Apr 15;377:578067. doi: 10.1016/j.jneuroim.2023.578067. Epub 2023 Mar 17. PMID: 36965365
HIV-1 shows extensive genetic diversity, HIV-1 subtype C being the most dominant subtype in the world. Our hypothesis is the frequency of CSF CD3(+)CD56(+) and CD3(-)CD56(dim) is reduced in HIV-1C compared to HIV-1B due to the Tat … 
 
Definition of a New HLA B*52-Restricted Rev CTL Epitope Targeted by an HIV-1-Infected Controller.
El Kenz B, Schmidt KG, Ogungbemi-Alt VK, Bergmann S, Steininger P, Korn K, Spriewald B, Harrer EG, Nganou-Makamdop K, Harrer T. Viruses. 2023 Feb 18;15(2):567. doi: 10.3390/v15020567. PMID: 36851781 Free PMC article.
The analysis of T-cell responses in HIV-1-infected controllers may contribute to a better understanding of the protective components of the immune system. Here, we analyzed the HIV-1-specific T-cell response in a 59-year-old HIV-1-infecte 
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Non-B subtypes account for a large proportion of clustered primary HIV-1 infections in Italy.
Bozzi G, Fabeni L, Abbate I, Berno G, Muscatello A, Taramasso L, Fabbiani M, Nozza S, Tambussi G, Rusconi S, Giacomelli A, Focà E, Pinnetti C, d'Ettorre G, Mussini C, Borghi V, Celesia BM, Madeddu G, Di Biagio A, Ripamonti D, Squillace N, Antinori A, Gori A, Capobianchi MR, Bandera A; INACTION study group. Sex Transm Infect. 2023 Feb;99(1):53-56. doi: 10.1136/sextrans-2021-055289. Epub 2022 Apr 20. PMID: 35443987 Free article.
OBJECTIVES AND DESIGN: Using pol sequences obtained for routine resistance testing, we characterised the molecular patterns of HIV-1 transmission and factors associated with being part of a transmission cluster among individuals who in 2008-2014 presented with prima … 
 
Humanized V(D)J-rearranging and TdT-expressing mouse vaccine models with physiological HIV-1 broadly neutralizing antibody precursors. 
 
Luo S, Jing C, Ye AY, Kratochvil S, Cottrell CA, Koo JH, Chapdelaine Williams A, Francisco LV, Batra H, Lamperti E, Kalyuzhniy O, Zhang Y, Barbieri A, Manis JP, Haynes BF, Schief WR, Batista FD, Tian M, Alt FW. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2217883120. doi: 10.1073/pnas.2217883120. Epub 2022 Dec 27. PMID: 36574685 Free PMC article.
V(D)J junctional regions encode complementarity-determining-region 3 (CDR3), an antigen-contact region immensely diversified through nontemplated nucleotide additions ("N-regions") by terminal deoxynucleotidyl transferase (TdT). HIV-1 vaccine strategies seek to elic …
 
Wang Y, Noël-Romas L, Perner M, Knodel S, Molatlhegi R, Hoger S, Birse K, Zuend CF, McKinnon LR, Burgener AD. Clin Infect Dis. 2023 Apr 17;76(8):1372-1381. doi: 10.1093/cid/ciac938. PMID: 36504254 Free PMC article. Clinical Trial.  DOI: 10.1093/cid/ciac938
BACKGROUND: HIV susceptibility, microbiome, youth.

Adverse Impact of HIV-1 on Long-term Outcomes Following HCV DAA Treatment: Final Results of ACTG A5320, the Viral Hepatitis C Infection Long-term Cohort Study (VHICS).
Wyles DL, Kang M, Matining RM, Murphy RL, Peters MG. Open Forum Infect Dis. 2023 Mar 6;10(3):ofad115. doi: 10.1093/ofid/ofad115. eCollection 2023 Mar. PMID: 37008564 Free PMC article.
BACKGROUND: Long-term outcome data after hepatitis C virus (HCV) treatment are limited, particularly for comparisons between persons with and without HIV. ...RESULTS: Three hundred thirty-two participants enrolled: 184 with HIV/HCV (130 SVR) and 148 with HCV … 
 
Clinical-Epidemiological Characteristics and IFITM-3 (rs12252) Variant Involvement in HIV-1 Mother-to-Children Transmission Susceptibility in a Brazilian Population.
Leandro DB, Celerino da Silva R, Rodrigues JKF, Leite MCG, Arraes LC, Coelho AVC, Crovella S, Zupin L, Guimarães RL. Life (Basel). 2023 Jan 31;13(2):397. doi: 10.3390/life13020397. PMID: 36836754 Free PMC article.
Mother-to-children transmission (MTCT) is the main infection route for HIV-1 in children, and may occur during pregnancy, delivery, and/or postpartum. ...This study aims at analyzing the influence of clinical epidemiological characteristics and a variant (rs12252) i … 
 
Circulation of Human Immunodeficiency Virus 1 A6 Variant in the Eastern Border of the European Union-Dynamics of the Virus Transmissions Between Poland and Ukraine.
Serwin K, Chaillon A, Scheibe K, Urbańska A, Aksak-Wąs B, Ząbek P, Siwak E, Cielniak I, Jabłonowska E, Wójcik-Cichy K, Jakubowski P, Bociąga-Jasik M, Witor A, Szetela B, Parczewski M. Clin Infect Dis. 2023 May 24;76(10):1716-1724. doi: 10.1093/cid/ciad058. PMID: 36857116
BACKGROUND: The human immunodeficiency virus (HIV) type 1 A6 variant is dominating in high-prevalence Eastern European countries, with increasing prevalence over the remaining regions of Europe. The recent war in Ukraine may contribute to further intro …
 
Structural requirements for class I MHC molecule-mediated antigen presentation and cytotoxic T cell recognition of an immunodominant determinant of the human immunodeficiency virus envelope protein.
Takahashi H, Houghten R, Putney SD, Margulies DH, Moss B, Germain RN, Berzofsky JA. J Exp Med. 1989 Dec 1;170(6):2023-35. doi: 10.1084/jem.170.6.2023. PMID: 2479705 Free PMC article.
The CTL-LINE specific for this HIV-1-IIIB-derived sequence could not recognize the HIV-1-RF variant-derived sequence from exactly the same site (315-329:--HIGPGRVIYATGQ). ...If the number of dominant HIV CTL epitopes is indeed very limite … 
 
Bispecific antibody CAP256.J3LS targets V2-apex and CD4-binding sites with high breadth and potency.
Zhang B, Gorman J, Kwon YD, Pegu A, Chao CW, Liu T, Asokan M, Bender MF, Bylund T, Damron L, Gollapudi D, Lei P, Li Y, Liu C, Louder MK, McKee K, Olia AS, Rawi R, Schön A, Wang S, Yang ES, Yang Y, Carlton K, Doria-Rose NA, Shapiro L, Seaman MS, Mascola JR, Kwong PD. MAbs. 2023 Jan-Dec;15(1):2165390. doi: 10.1080/19420862.2023.2165390. PMID: 36729903 Free PMC article.
Antibody CAP256-VRC26.25 targets the second hypervariable region (V2) at the apex of the HIV envelope (Env) trimer with extraordinary neutralization potency, although less than optimal breadth. ...CAP256.J3LS neutralized over 97% of a multiclade 208-strain panel (geometric …
Modeling the effects of drugs of abuse on within-host dynamics of two HIV species.
Uhl PM, Vaidya NK. J Theor Biol. 2023 Apr 7;562:111435. doi: 10.1016/j.jtbi.2023.111435. Epub 2023 Feb 9. PMID: 36764443 Free article.
Injection drug use is one of the most significant risk factors associated with contracting human immunodeficiency virus (HIV), and drug users infected with HIV suffer from a higher viral load and rapid disease progression. While replication of HIV may …
CRISPR-Cas9 editing of a TNPO3 mutation in a muscle cell model of limb-girdle muscular dystrophy type D2.
Poyatos-García J, Blázquez-Bernal Á, Selva-Giménez M, Bargiela A, Espinosa-Espinosa J, Vázquez-Manrique RP, Bigot A, Artero R, Vilchez JJ. Mol Ther Nucleic Acids. 2023 Jan 11;31:324-338. doi: 10.1016/j.omtn.2023.01.004. eCollection 2023 Mar 14. PMID: 36789274 Free PMC article.
A single-nucleotide deletion in the stop codon of the nuclear import receptor transportin-3 (TNPO3), also involved in human immunodeficiency virus type 1 (HIV-1) infection, causes the ultrarare autosomal dominant disease limb-girdle muscular dys …
Association of Toll-Like Receptor 3 Polymorphisms with Kaposi's Sarcoma-Associated Herpesvirus Infection Among Human Immunodeficiency Virus-Infected Individuals in Xinjiang, China.
Zhang X, Wu X, Wang H, Xu Y, Li Y, Chen T, Zhang T. Viral Immunol. 2023 May;36(4):290-297. doi: 10.1089/vim.2022.0177. Epub 2023 Apr 11. PMID: 37040285
We studied the effect of TLR3 polymorphisms on the risk of Kaposi's sarcoma-associated herpesvirus (KSHV) infection. A cross-sectional study was performed among human immunodeficiency virus (HIV)-infected individuals in Xinjiang, a KSHV-endemic region of Chin …
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