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måndag 22 maj 2023

GITHUB uutisiin tuli 4 tuntia sitten eräs japanilainen VUM -variantin sekvenssi. BA.2.75* linjasta. BN.1 alavarianttilinjan FR alalinja.

 https://github.com/cov-lineages/pango-designation/issues/2006

(Otan sitaatteja  tiedemieskeskustelusta: Tämä uusi alalinja on  "Centaurin  BA.2  linjojen    BA.2.75 jälkikasvusta. Kyse on omikronalalinjasta eikä rekombinantista ja   ne ovat monitoroitavia VUM ja monitorointilöytöjä). 

 B.1.1 529 alias omicron alias "BA"

 "FR": "B.1.1.529.2.75.5.1.2.3"  alias "BA.2.75.5.1.2.3" alias  "BN.1.2.3" 

FR.1. on sama kuin BN.1.1.2.3 .

"BN" tarkoittaa B.1.1.529.2.75.5 alias  BA.2.75.5

 Nimim. "Sinickle" ilmoittaa:

"Quick (in China) FR.1 ,Sublineage with S:P82H (46 Seqs - China, Japan) #2006

Description
Sub-lineage of: FR.1  (BN.1 + ORF1a:L293F, S:K187E, E:D72G, N:T366I)
Earliest sequence: 2023-4-07, Liaoning China
Most recent sequence: 2023-5-9, Sichuan China (current)
Countries circulating: 2 (China, Japan)
Number of Sequences: 46 (45 China, multiple provinces, 1 Japan)
GISAID AA Query: Spike_k356T, Spike_K187E, Spike_P82H
CovSpectrum Query:
Substitutions on top of FR.1: Spike:P82H"
 
" Discussion:
FR.1 appears to be a fair bit quicker than BN.1 in Japan. In China, with low sample size, FR.1 + S:P82H appears to be spreading a fair amount more quickly than traditional FR.1. S:P82H is possibly similar to XBB*'s S:V83A.
The mutations don't really stand out to me, but its apparent speed in China stands out quite a lot in my more objective tracking method, and its appearance in multiple provinces makes it less likely to be a cluster."

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