Esimerkki varianttien runsaasta haaroittumisista eri alalinjoiksi, jotka odottavat definitiotaan

 ( Tämä VUM-varianttilaatu  tuli GITHUB uutisiin 2 viikkoa sitten)

Two FL.1(XBB.1.9.1.1) branches with S:K478R (A22995G)

 

Branch A: 15 seqs
Defining mutations: FL.1>G25186T(S:Q1208H)>A22995G (S:K478R)
GISAID query: Spike_A701V, Spike_Q1208H, Spike_K478R
Earliest seq: 2023-03-16 (Australia, EPI_ISL_17358833)
Most recent seq: 2023-04-19 (Vietnam, EPI_ISL_17614077)
Countries detected: Vietnam (6), Australia (5), USA (3), South Korea (1)

the 6 seqs from Vietnam are updated today. 10 of 15 seqs are updated in May, and 3 of 15 also get T23005A (S:N481K)

 Branch B: 7 seqs
Defining mutations: FL.1>T6148A>G25696C (ORF3a:E102Q)>A24670G>A22995G (S:K478R), G25266T (S:C1235F), G29179C, C29311T
GISAID query: Spike_A701V, Spike_K478R, T6148A
Earliest seq: 2023-02-27 (Indonesia, EPI_ISL_17332707)
Most recent seq: 2023-04-12 (Indonesia, EPI_ISL_17518063)
Countries detected: Indonesia (7)

- Branch A is more worthy of monitoring as the recent growth and spread into 4 countries.

 -Let's wait until they are at least 25 sequences, ping me then-

 -About branch A i would highlight that we have just 99 Vietnam related sequences collected after 10th of April , and this is 7 out 99 with XBB.1.16  (VOI)  at 37 and XBB.1.5.42 (VOI)  at 17 , Vietnam is experimenting a sharp increase of cases and i would blame this 3 lineages for that . I would designate immediately Branch A.

(query G25186T, C22995G, T28297C finds 19)