Verrattuna Sars1 virukseen SARS-2 on kehittänyt itselleen peptidiä, joka omaa CendR elementin
SARS2 wt CASYQTQTNSPRRARSVASQST insertio
mutaatio P681R tai P681H
SARS2 wt 671 CASYQTQTNS RRRARSVASQ ST 692
insertiokohtaan mutaatio P =R
671 CASYQTQTNS HRRARSVASQ ST
insertiokohtan mutaaio P=H
c-end Rule elementtiainesta
Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16157–16162.
Published online 2009 Sep 2. doi: 10.1073/pnas.0908201106
PMCID: PMC2752543
PMID: 19805273
Applied Biological Sciences
C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration
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