Neuropiliini 1 peptidi

 

1. NM_001244972.2 → NP_001231901.2  neuropilin-1 isoform d precursor

   ORIGIN      
           1 merglpllca vlalvlapag afrndkcgdt ikiespgylt spgyphsyhp sekcewliqa
          61 pdpyqrimin fnphfdledr dckydyvevf dgenenghfr gkfcgkiapp pvvssgpflf
         121 ikfvsdyeth gagfsiryei fkrgpecsqn yttpsgviks pgfpekypns lectyivfvp
         181 kmseiilefe sfdlepdsnp pggmfcrydr leiwdgfpdv gphigrycgq ktpgrirsss
         241 gilsmvfytd saiakegfsa nysvlqssvs edfkcmealg mesgeihsdq itassqystn
         301 wsaersrlny pengwtpged syrewiqvdl gllrfvtavg tqgaisketk kkyyvktyki
         361 dvssngedwi tikegnkpvl fqgntnptdv vvavfpkpli trfvrikpat wetgismrfe
         421 vygckitdyp csgmlgmvsg lisdsqitss nqgdrnwmpe nirlvtsrsg walppaphsy
         481 inewlqidlg eekivrgiii qggkhrenkv fmrkfkigys nngsdwkmim ddskrkaksf
         541 egnnnydtpe lrtfpalstr firiyperat hgglglrmel lgceveapta gpttpngnlv
         601 decdddqanc hsgtggttvl atekptvids tiqsefptyg fncefgwgsh ktfchwehdn
         661 hvqlkwsvlt sktgpiqdht agdgnfiysq adenqkgkva rlvspvvysq nsahcmtfwy
         721 hmsgshvgtl rvklryqkpe eydqlvwmai ghqgdhwkeg rvllhkslkl yqvifegeig
         781 kgnlggiavd disinnhisq edcakpadld kknpeikide tgstpgyege gegdknisrk
         841 pgnvlktldp ilitiiamsa lgvllgavcg vvlycacwhn gmsernlsal enynfelvdg
         901 vklkkdklnt qstysea

    

   Status: REVIEWED

   Description

   Transcript Variant: This variant (4) uses two different splice sites in the coding region, compared to variant 1. The resulting protein (isoform d) is shorter when it is compared to isoform a.

   Source sequence(s)

   AL121748, AL353600

   Conserved Domains (4) summary

   smart00137
   Location:638 → 798

   MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others) (synonyme  RPTPmu
   

   cd00041
   Location:27 → 140

   CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

   cd00057
   Location:277 → 423

   FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

   pfam11980
   Location:839 → 917

   DUF3481; C-terminal domain of neuropilin glycoprotein