Ebolavirusprotein VP24 prevents transcription of STAT1, thus hindering IFN mediated broad antiviral immune response

Here’s how Ebola affects the immune system
Researchers showed the Ebola virus protein called VP24 is responsible for actually disrupting the cell’s innate or natural immune response, making it extremely deadly. VP24 directly prevents the transcription factor STAT1, which carries interferon’s antiviral message, from entering the nucleus and initiating an immune response. According to Chris Basler of the Icahn School of Medicine at Mount Sinai, once we figure out how VP24 promotes this disruption new ways to defeat the virus could be explored.
http://jvi.asm.org/content/80/11/5168.abstract