Sars-Cov-2 rekombinanttivarianttien löytöjä edelleen. eräs iso XBB.1.5 alalinja ryväs selvittelyssä

 Tämä XBB.1.5  diversiteetin linja on ollut  XBB.1.5.40 merkkaatujen joukossa ja selvästi alkanut  erottua ja nyt sitä selvitellään tarkemmin. Näitä on 1848 sekvenssiä  selvittelyssä ja alajakoa vailla tällä hetkellä. 

https://github.com/cov-lineages/pango-designation/issues/2082

Recently spreading XBB.1.5 Branch designation request , three levels already. #2082

Gueli opened this issue Jul 3, 2023 · 3 comments

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FedeGueli commented Jul 3, 2023 •

cc (at) corneliusroemer (at) NkRMnZr found first and i independently rediscovered an undesignated branch of XBB.1.5 that seems beeing disproportionately sampled from MAY ahead and it is acquiring interesting new mutations and spreading in Spain Asia and Worlwide. The first, valid, description of it is in this proposal : sars-cov-2-variants/lineage-proposals#307 full credit to (at) NkRMnZr I sum it just to finalize its designation as soon as possible. .1 It is a XBB.1.5 branch , missassigned by Nextclade to XBB.1.5.40 It is defined by XBB.1.5 >> Orf1a:S771I ( G2577T) Its query is : G2577T,T17124C finds 1848 , 385 from May 2023 ahead .1.1 then its first sublineage is defined by XBB.1.5 >> Orf1a:S771I ( G2577T) >> Orf1a:N2140S ( A6684G ) Gisaid : A6684G,G2577T,T17124C finds 897 sequences 247 of them collected after MAY 1 .1.1.1 this branch has a big sublineage defined by XBB.1.5 >> Orf1a:S771I ( G2577T) >> Orf1a:N2140S ( A6684G )>> Orf7a:K2E (A27397G) Gisaid: A6684G,G2577T,T17124C,A27397G finds 375 100 of them collected after MAY 1 .1.2 then there is a second sublineage of Orf1a:S771I defined by a nuc mutations XBB.1.5 >> Orf1a:S771I ( G2577T) >> C5512T Gisaid query: ,G2577T,T17124C,C5512T finds 659 113 collected after MAY.1 1.2.1 this branch has a sublineage defined by Orf1a:T882I (C2910T) & S:P621A (C23423G) Gisaid query : T17124C,C5512T,C23423G finds 32 all collected from MAY ahead 1.2.2 this branch is defined by C5512T + C8752T + S:E654K (G23522A) Gisaid query: G23522A,C8752T,C5512T finds 15 all from MAY ahead (proposed here sars-cov-2-variants/lineage-proposals#311 ) Further sublineages: Then there are the proposals of further sublineages the one proposed by @NkRMnZr in sars-cov-2-variants/lineage-proposals#307 ALL the sublineages discsussed highlighted here: Light green = .1 Orange = .1.1 Grey = .1.1.1 Red = 1.2 Green: 1.2.1 S:P621A Yellow = 1.2.2 E:654K

( KATSO LINKISTÄ  linjojen puu)  Phylogenetic tree

https://user-images.githubusercontent.com/87669813/250539156-af67a145-27d5-40c2-a85c-bda757a4b2c2.png