WHO tilannekatsaus COVID-19 vaiheesta tullut 29.6. 2023 sekä 6.7. 2023 ( viikoilta 23- 24)

Lisäys 9.7. 2023  Päivitystä WHO edit. 150,  6.7 2023

 https://www.who.int/publications/m/item/weekly-epidemiological-update-on-covid-19---6-july-2023

 

 https://www.who.int/emergencies/situation-reports

Overview

Globally, over one million new cases and over 5700 deaths were reported in the last 28 days (29 May to 25 June 2023). While five WHO regions have reported decreases in both cases and deaths, the African Region has reported a decrease in cases but an increase in deaths. As of 25 June 2023, over 767 million confirmed cases and over 6.9 million deaths have been reported globally. Reported cases are not an accurate representation of infection rates due to the reductions in testing and reporting globally. During this 28-day period, only 62% (146 of 234) of countries and territories reported at least one case – a proportion that has been declining since mid-2022.

In this edition, we include:

• The COVID-19 epidemiological update at the global and the regional levels
• An update on hospitalizations and ICU admissions
• An update on the SARS-CoV-2 variants of interest (VOI) and variants under monitoring (VUM)

Some countries continue to report high burdens of COVID-19, including increases in newly reported cases and, more importantly, increases in hospitalizations and deaths – the latter of which are considered more reliable indicators given the reductions in testing.
We present changes in epidemiological trends using a 28-day interval. Disaggregated data are still accessible on the WHO COVID-19 dashboard, where the full dataset is available for download. Global and national data on SARS-CoV-2 PCR percent positivity are available on WHO’s integrated dashboard provided by the Global Influenza Programme 

( Several countries are now being updated using data from the European Surveillance System (TESSy). As a result, for some of these countries, the numbers have been revised retrospectively, leading to reduced figures in certain instances. Consequently, the cumulative totals are now lower compared to the figures reported in the COVID-19 Weekly Epidemiological Update published on 22 June 2023).

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Figure 1. COVID-19 cases reported by WHO Region, and global deaths by 28-day intervals, as of 25 June 2023**
**See Annex 1: Data, table, and figure note

At the regional level, the number of newly reported 28-day cases decreased across all six WHO regions: the Eastern Mediterranean Region (-75%), the South-East Asia Region (-73%), the Region of the Americas (-66%), the European Region (-57%), the Western Pacific Region (-35%), and the African Region (-12%). 

The number of newly reported 28-day deaths decreased across five regions: the Region of the Americas (-68%), the Eastern Mediterranean Region (-63%), the European Region (-62%), the South-East Asia Region (-56%), and the Western Pacific Region (-43%); while newly reported deaths increased in the African Region (+20%).

 
At the country level, the highest numbers of new 28-day cases were reported from the Republic of Korea (371 513 new cases; -22%), Australia (111 543 new cases; -21%), Brazil (77 022 new cases; -41%), France (45 306 new cases; -55%), and Singapore (40 531 new cases; -56%). 

The highest numbers of new 28-day deaths were reported from Brazil (1055 new deaths; -10%), the Russian Federation (517 new deaths; -16%), Australia (343 new deaths; -53%), Italy (342 new deaths; -48%), and France (285 new deaths; -58%).

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 Hospitalizations and ICU admissions

At the global level, during the past 28 days (22 May 2023 to 18 June 2023), a total of 62 128 new hospitalizations and 2080 new intensive care unit (ICU) admissions were reported (Figure 4). This represents a 40% and 48% decrease in both hospitalizations and ICU admissions, respectively, compared to the previous 28 days (24 April 2023 to 21 May 2023). The presented hospitalization data are preliminary and might change as new data become available.
Furthermore, hospitalization data are subject to reporting delays. These data also likely include both hospitalizations with incidental cases of SARS-CoV-2 infection and those due to COVID-19 disease.
Globally, during the past 28 days, 40 (17%) countries reported data to WHO on new hospitalizations at least once
(Figure 5). 

The European Region had the highest proportion of countries reporting data on new hospitalizations (20 countries; 33%), followed by the Region of the Americas (eight countries; 14%), the African Region (four countries; 8%), the Eastern Mediterranean Region (three countries; 14%), the Western Pacific Region (three countries; 9%), and the South-East Asia Region (two countries; 20%). The proportion of countries that consistently ii reported new hospitalizations for the period was 10% (24 countries) (Table 2).
Among the 24 countries consistently reporting new hospitalizations, three (13%) countries registered an increase of 20% or greater in hospitalizations during the past 28 days compared to the previous 28-day period: Afghanistan (178 vs 33; +439%), Bangladesh (269 vs 104; +159%), and Malta (86 vs 35; +146%). The highest number of new hospitalizations was reported from the United States of America (27 065 vs 37 232; -27%), Ukraine (5744 vs 8853; -35%), and France (3634 vs 7642; -52%).
Across all six WHO regions, in the past 28 days, a total of 30 (13%) countries reported data to WHO on new ICU admissions at least once (Figure 5). The European Region had the highest proportion of countries reporting data on new ICU admissions (17 countries; 28%), followed by the Western Pacific Region (five countries; 14%), the Region of the Americas (four countries; 7%), the Eastern Mediterranean Region (two countries; 9%), the African Region (one country; 2%), and the South-East Asia Region (one country; 10%) The proportion of countries that consistently reported new ICU admissions for the period was 8% (18 countries) (Table 2).
Among the 18 countries consistently reporting new ICU admissions, two (11%) countries showed an increase of 20% or greater in new ICU admissions during the past 28 days compared to the previous 28-day period: Lithuania (19 vs 11; 73%) and Mexico (19 vs 14; +36%). The highest numbers of new ICU admissions were reported from France (438 vs 866; -49%), Australia (304 vs 325; -6%), and Ukraine (164 vs 280; -41%).
ii “Consistently” as used here refers to countries that submitted data for new hospitalizations and intensive care unit admissions for the four consecutive weeks that make up the 28-day period.

( Figures: Declining  skenario. Look maps in WHO link!)

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SARS-CoV-2 variants of interest (VOI)  and variants under monitoring (VUM)

Geographic spread and prevalence
Globally, from 29 May to 25 June 2023 (28 days), 13 152 SARS-CoV-2 sequences were shared through GISAID. WHO is currently tracking two variants of interest (VOIs), XBB.1.5 and XBB.1.16, along with six variants under monitoring (VUMs) and their descendent lineages. The VUMs are BA.2.75, CH.1.1, XBB, XBB.1.9.1, XBB.1.9.2, and XBB.2.3.

 

Globally, 114 countries have reported the detection of XBB.1.5 (VOI)  since its emergence. Its prevalence has been declining steadily. In epidemiological week 23 (5 to 11 June 2023), XBB.1.5 accounted for 19.8% of sequences, as compared to 32.1% in week 19 (8 to 14 May 2023). The updated risk assessment for XBB.1.5 presents supplementary laboratory and epidemiological evidence, which suggests that XBB.1.5 does not pose additional public health risks compared to other circulating variants.

 

XBB.1.16 (VOI)  has been reported from 89 countries. In week 23, XBB.1.16 (VOI)  accounted for 20.5% of sequences, an increase from 15.7% in week 19. Its prevalence has surpassed that of XBB.1.5 in week 23. An analysis of available data indicates that countries with a low prior prevalence of XBB.1.5 have experienced a significant increase in the prevalence of XBB.1.16, while

countries that had a high prevalence of XBB.1.5 have reported low circulation of XBB.1.16.

Table 3 shows the number of countries reporting the VOIs and VUMs and their prevalence from week 19 to week 23.

Table 3. Weekly prevalence of SARS-CoV-2 VOIs and VUMs, week 19

The VOI and the VUMs that have shown increasing trends during the last five weeks period are highlighted in orange, those that have remained stable are highlighted in blue, while those with decreasing trends are highlighted in green. Among the VUMs,
XBB, XBB.1.9.2, and XBB.2.3 have shown increasing trends in recent weeks. Overall, other VUMs show declining or stable trends during the same reporting period.

Table 3. Weekly prevalence of SARS-CoV-2 VOIs and VUMs, week 19 to week 23 of 2023
Lineage Countries§ Sequences§ 2023-19 2023-20 2023-21 2023-22 2023-23    2023 24
XBB.1.5*  114      242 397       32.16        29.66      24.81       22.26      19.79
XBB.1.16*  89       27 413        15.66        18.06     18.67        21.31      20.53
BA.2.75*  124      119 879          3.45           2.91      2.66          2.46         1.64
CH.1.1*     95         41 989          1.36          1.23       0.95          0.92         1.11
XBB*      130         62 221          4.75           5.01       5.61          5.82         6.37
XBB.1.9.1* 98       40 414         18.29        18.56     19.02       18.82        19.52
XBB.1.9.2* 79       20 604         10.32        10.52      12.03      12.15        12.18
XBB.2.3   * 60         5 769           2.79           3.38       4.23         4.31         4.06
Unassigned 91     146 918           0.99           1.09        1.46         2.52         4.70
Other+ 209        6 746 112          8.89           8.72        9.43         8.40         9.09
* Includes descendant lineages, except those individually specified elsewhere in the table. For example, XBB* does not include XBB.1.5, XBB.1.9.1, XBB.1.9.2, XBB.1.16, and XBB.2.3.
+ Others are other circulating lineages excluding the VOI, VUMs, BA.1*, BA.2*, BA.3*, BA.4*, BA.5*.
§ Number of countries and sequences are since the emergence of the variants
 

Additional resources
• Tracking SARS-CoV-2 Variants
• WHO statement on updated tracking system on SARS-CoV-2 variants of concern and variants of interest
• WHO XBB.1.5 Updated Risk Assessment, 20 June 2023
• WHO XBB.1.16 Updated Risk Assessment, 5 June 202

Lisäystä edelliseen taulukkoon 6.7. 2023 päivityksestä:Poimin numeooita esiin. Raportoivat maat vähentyneet edelleen pandemian käyrän laskiessa.

https://www.who.int/publications/m/item/weekly-epidemiological-update-on-covid-19---6-july-2023
Table 3. Weekly prevalence of SARS-CoV-2 VOIs and VUMs, epidemiological week 20 to week 24 of 2023. VOI variantit ovat edelleen samat  XBB.1.5* ja XBB.1.16*

 
Lin,             Cntr,§   Seqs§     2023-20 2023-21 2023-22 2023-23  2023-24
XBB.1.5*    115     250 410   30.14     26.66      22.56     21.12       16.26
XBB.1.16*   91        31 367   18.12     18.59     20.53      21.70       21.18
BA.2.75*   124       121 110    2.91       2.64       2.71         2.27         2.33
CH.1.1*       95         42 312    1.12       0.89       0.88         0.83         0.78
XBB*        130         63 467    4.95       5.61       5.80         6.68         7.46
XBB.1.9.1* 98        43 728   18.24    18.20      18.37       18.00       16.04
XBB.1.9.2* 82        22 645   10.26    11.43      12.70       11.85       12.68
XBB.2.3*    63         6 522      3.47      4.10        4.26        3.93         4.25
Unassigned 92      149 333     0.97      1.29        1.88        2.73          6.36
Other      +209   6 751 730     8.95      9.53        9.35        9.97        11.97
* Includes descendant lineages, except those individually specified elsewhere in the table. For example, XBB* does not include XBB.1.5, XBB.1.9.1,
XBB.1.9.2, XBB.1.16, and XBB.2.3.
+ Others are other circulating lineages excluding the VOI, VUMs, BA.1*, BA.2*, BA.3*, BA.4*, BA.5*.
§ Number of countries and sequences are since the emergence of the variants