https://www.ncbi.nlm.nih.gov/books/NBK539787/
Tässä luettelossa ei mainita POXviruksia, mutta käytännössä esiintyy Hiv-1 immuunivajeessa myös Molluscum contagiosum infektioita kirjallisuuden mukaan.
HAKU: HIV-1 AND POXvirus Molluscum contagiosum
13 vastausta: Otan siaatin
Molluscum contagiosum: recent advances in pathogenic mechanisms, and new therapies.
Am J Clin Dermatol. 2002;3(8):535-45. doi: 10.2165/00128071-200203080-00004.
PMID: 12358555
Review.
Two poxviruses, Molluscum contagiosum
virus (MCV) and Variola virus are specific to humans. ...Rupture and
discharge of the virus-packed cells occurs in a process similar to
membrane debris and MCV accumulate in the crater-like ostium; MCV
infection is spread by con …
Molluscum contagiosum virus: antibody responses in persons with clinical lesions and seroepidemiology in a representative Australian population.
J Infect Dis. 1999 Mar;179(3):701-4. doi: 10.1086/314620.
PMID: 9952381
An ELISA for molluscum contagiosum virus
(MCV) was used to determine the antibody status of 35 adults with
clinical infections and known human immunodeficiency virus (HIV) serology and of 357 persons (ages, 1 week-69 years) considered representative of …
Molluscum contagiosum and human immunodeficiency virus.
Arch Dermatol. 1992 Oct;128(10):1407-8.
PMID: 1417038
No abstract available.
Rapid microtiter assays for poxvirus topoisomerase, mammalian type IB topoisomerase and HIV-1 integrase: application to inhibitor isolation.
Nucleic Acids Res. 2000 Dec 15;28(24):4884-92. doi: 10.1093/nar/28.24.4884.
PMID: 11121479
Free PMC article.
These assays were used to screen compound libraries for inhibitors active against mammalian topoisomerase or HIV
integrase. We identified (-)-epigallocatechin 3-O:-gallate, as a potent
inhibitor of religation by mammalian topoisomerase (IC(50) of 26 nM),
potentially explai …
Imiquimod therapy for molluscum contagiosum.
J Cutan Med Surg. 2000 Apr;4(2):76-82. doi: 10.1177/120347540000400207.
PMID: 11179929
BACKGROUND: Molluscum contagiosum virus (MCV) is a large double-stranded DNA virus that is a member of the family Poxviridae, and which has a worldwide distribution. ...Imiquimod appeared to be the most efficacious in patients with HIV-1 disease …
Clinical potential of the acyclic nucleoside
phosphonates cidofovir, adefovir, and tenofovir in treatment of DNA
virus and retrovirus infections.
Clin Microbiol Rev. 2003 Oct;16(4):569-96. doi: 10.1128/CMR.16.4.569-596.2003.
PMID: 14557287
Free PMC article.
Review.
The acyclic nucleoside phosphonates HPMPC (cidofovir),
PMEA (adefovir), and PMPA (tenofovir) have proved to be effective in
vitro (cell culture systems) and in vivo (animal models and clinical
studies) against a wide variety of DNA virus and retrovirus infections:
cidofovir again …
Molluscum contagiosum. Ultrastructural
evidence for its presence in skin adjacent to clinical lesions in
patients infected with human immunodeficiency virus type 1. Military Medical Consortium for Applied Retroviral Research.
Arch Dermatol. 1992 Feb;128(2):223-7. doi: 10.1001/archderm.128.2.223.
PMID: 1739301
Both routine histopathologic examination and
ultrastructural examination were performed in two patients infected with
human immunodeficiency virus type 1 (HIV-1) and three non-HIV-1-infected patients. RESULTS: All patients showed histologic chan …
Prenylation of viral proteins by enzymes of the host:
Virus-driven rationale for therapy with statins and FT/GGT1 inhibitors.
Bioessays. 2017 Oct;39(10). doi: 10.1002/bies.201700014. Epub 2017 Sep 8.
PMID: 28885709
Review.
Using extensively validated high-confidence prenylation
predictions by PrePS with a cut-off for experimentally confirmed
farnesylation of hepatitis delta virus antigen, we compiled in silico
evidence for several new prenylation candidates, including IRL9 (CMV)
and few other prote …
Lamellarin alpha 20-sulfate, an inhibitor of HIV-1 integrase active against HIV-1 virus in cell culture.
J Med Chem. 1999 Jun 3;42(11):1901-7. doi: 10.1021/jm9806650.
PMID: 10354398
HIV-1 integrase is an attractive
target for anti-retroviral chemotherapy, but to date no clinically
useful inhibitors have been developed. ...Lamellarin alpha 20-sulfate
also inhibited integration in vitro by authentic HIV-1 replication intermediates i …
Bioorg Med Chem. 2002 Oct;10(10):3285-90. doi: 10.1016/s0968-0896(02)00237-7.
PMID: 12150874
Lamellarin alpha does not inhibit HIV-1
integrase but shows moderate cytotoxicity with good cell line
selectivity. Lamellarin alpha 13,20-disulfate is a moderate inhibitor of
both HIV-1 integrase and cancer cell lines. Lamellarin H is a more potent inh …
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