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lördag 14 januari 2023

H5N1 päivitys 1.3.2023 ...unohtamatta zoonoottisia kierteleviä lintuviruksia...

https://www.woah.org/app/uploads/2022/03/avian-influenza-0.pdf

Sitaattia: 

4| Scientific Task Force on Avian Influenza and Wild Birds

 
Current situation


HPAI viruses of the original goose/Guangdong/96 (Gs/Gd) lineage, predominantly H5N1 and H5N8, have continued to circulate in Asia, Africa and Europe following the resurgence of extensive outbreaks since October 2021 3,4,5,6.

The epizootic at that time in Europe, caused by viruses of the 2.3.4.4b clade, was considered unprecedented. This lineage can be considered particularlyfit’, and indeed unusually there were detections of these viruses in the summer months in wild birds (as well as poultry) in Europe, indicating continued circulation of virus in wild birds during this time 7.

 Pivitystieto: Lauma vedessäeläviä  nisäkkäitä  hylkeentapaisia merileijjonia  kuollut  samassa yhteydessä kun ollut kymmenin tuhansin lintuinfluenssakuolemia linnustossa Perussa: 

Jotain tällaisia eläimiä isohko määrä: ensimmäinen tieto ruotsin lehdistössä 8.2. 2023 aikaan, kun  näitä eläimiä oli kuollut runsaat 500 perun  rannoille. . 



Animalia  
  Taxonomic Rank: Family  
  Synonym(s): Arctocephalinae
 
    Otariinae Gray, 1825
 
  Common Name(s): eared seals [English]
 
    sea lions [English]
 
     

https://www.itis.gov/servlet/SingleRpt/SingleRpt?search_topic=TSN&search_value=180615#null 

Tämä toistettu uutinen oli radiosa 28.2. 2023   ja satuin kuulemaan, joten kirjoitan sitaatin:

"En muterad variant av fågelinfluensan tros ligga bakom de hundratals döda eller döende sjölejon, som hittats på stränderna i Peru. Hör Sara Heyman, Ekots globala hälsokorrespondent.
Innehåller
  • Fågelinfluensan kan ha muterat
  • 600 döda sjölejon tros ha ätit smittad fågel
  • Unikt: Endast andra djur i fångenskap har smittats tidigare
  • Kan orsaka organsvikt och dödsfall
  • Inget botemedel finns
  • WHO manar till lugn – men smittspridningen ökar
  • En nyhetsfördjupning från Ekot

Pablo Dalence"

Mainitaan, että  lintuinfluenssa virusolisi ehkä mutatoitunut. Tässä ei mainita suoraan  sitä  H5N1, muta todennäköisesti   kyse on siitä. Missä kombinaatiossa se nyt siten on, eiole tietoa. Päasia on se, että H5N1 ei ole käynyt ihmiskuntaa läpi, joten se tulee olemaan pandeminen,tosin se muoto missä se siinä vaiheesa on ,ei ole vielä tiedossa. 

 

14.1.2023

Although H5N8 HPAI is still responsible for poultry and wild bird cases mainly in Asia, H5N1 has now in effect replaced this subtype in Africa and Eurasia in both poultry and wild birds.

The wide range of wild birds affected including

wildfowl,

waders,

gulls,

cranes,

grebes,

herons,

pelicans,

gamebirds,

corvids

and raptors (diurnal and nocturnal),

in addition to sporadic cases in mammals such as

red fox Vulpes vulpes,

Eurasian otter Lutra lutra

and harbour Phoca vitulina

and grey seal Halichoerus grypus

3,

indicates the potential for multiple and complex negative ecological impacts.


As an example of unusual timing, location and host species, during the summer of 2021, beginning in July, a number of

great skuas Catharacta skua

were reported with H5N1 HPAI in the far northern Scottish Islands 7.


In a more typical pattern, the number of wild bird and poultry reports of infection increased during the autumn/ winter months of 2021. Notable wild bird outbreaks involving H5N1 HPAI include deaths in November of

approximately 300

demoiselle cranes Anthropoides virgo

in Rajastan, India 8,9.


[At time of writing some of the recent wild bird mortality events are not yet reported in
the scientific literature.]


In the UK, mass mortality has been described on the Solway Firth in South West Scotland 10.


Beginning in early November 2021,

barnacle geese Branta leucopsis

were seen to be dying. Although other species such as

waders and other wildfowl have been affected 11,

the large population of Svalbard-breeding barnacle geese has been the focus of the epizootic, with some 8,000-10,000 estimated dead to date.


At time of writing, over 20 % of the total flyway population is estimated to have died. The
same species, but of other populations, was particularly affected during the previous winter in continental Europe 3.


In The Netherlands, H5N1 HPAI has been associated with the death of

hundreds of red knot Calidris canutus and other waders near Schiermonnikoog (Waddensea) in December 2021 12. Notably red knot were severely affected by H5N8 HPAI last winter in The Netherlands.

The Hula Valley region of Israel has witnessed mass mortality beginning in December 2021 involving deaths of some 8,000

common cranes Grus grus 13.


Globally threatened species such as

marbled teal Marmaronetta angustirostris have died, as have hundreds of

great white pelicans Pelecanus onocrotalus (the victims of large-scale
die-offs in West Africa in December-January 2020-21 and at other sites in Europe 6).


Despite significant operations to remove carcasses and hence reduce infection pressure,
concerns remain for those cranes wintering further south in north east Africa that will use the Hula Valley as a staging site during spring migration.


Of additional concern, in terms of potential for wider geographical spread in the Americas, is the first detection of the same lineage of virus in Newfoundland, Canada, in December 2021, and in hunted wildfowl in the eastern USA reported in January 2022.

The afore mentioned cases in
skuas (which in effect act like raptors and likely represent sentinels of infection in other birds), and the detection of the same virus in the gulls in Newfoundland, suggest wild bird movements being involved in the introduction to the Americas 7.


In terms of human health, the currently circulating H5N1 HPAI viruses do not apparently pose the same zoonotic risk as the original’ Asian lineage H5N1 (clade 2.2 and their derivatives plus clade 2.3.4.4b H5N6 viruses currently in China). In general, the risk can be considered low, recognising that some agencies now consider occupational exposure, e.g. those working on poultry culling operations, as low/moderate 3.


The scale of mortality across Europe and parts of Asia, plus the findings of asymptomatic carriage of infection in some duck and goose species 1

has again indicated that wild birds can be both victims and vectors of infection.


Lack of robust surveillance and contextual information surrounding many of the wild bird deaths continues to prevent good epidemiological understanding. Studies such as that of Kleyheeg et al. (2017), which at least attempt to quantify mortality and its potential impacts, by working across both wild bird and virology monitoring sectors, are to be encouraged.


Continued evolution of the
Gs/Gd lineage viruses in the last several years has occurred in both poultry and wild bird populations. Whilst there is continued maintenance in both ‘populations’ this process will still remain dynamic and is likely to involve further changes in the virus.


Spread of HPAI viruses from poultry or between wild birds, with consequent co-circulation of low pathogenic AI viruses naturally maintained in wild birds, can give rise to new virus variants through genetic recombination 1.


The emergence and spread of such variants is a dynamic on-going process that is likely influenced by species susceptibility, population structure and immunity, behaviour, virus fitness and environmental conditions.


In summary, a disease once essentially confined to the poultry sector which spread most significantly to wildlife in 2005, is now again, responsible for regular large-scale losses of wildlife and repeated spillback to poultry with consequent significant impacts and threats.


As pressures on biodiversity continue, and noting calls for reassessment of the poultry sector, this One Health issue requires cross-sectoral working and responses to ensure
conservation obligations are met and health of people, livestock and wildlife is protected



3 EFSA (2021)
4 FAO website - avian influenza situation updates
5 OIE website - avian influenza
6 Scientific Task Force on Avian Influenza and Wild Birds statement, February 2021
7 Caliendo
et al. (2022)
8 Times of India
9 https://promedmail.org/promed-post/?place=8700509,317#promedmailmap
10 https://www.bbc.co.uk/news/uk-scotland-south-scotland-59669263
11 https://www.gov.uk/government/publications/avian-influenza-bird-flu-in-europe
12 https://www.wur.nl/nl/Onderzoek-Resultaten/Onderzoeksinstituten/Bioveterinary-Research/show-bvr/Vogelgriep-bij-wilde-vogels.htm
13 https://www.birdlife.org/news/2022/01/10/israel-and-uk-facing-record-breaking-bird-flu-outbreaks


 

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