Sars-Cov-2 , Omicron, BQ.1.1.35 alias "ET" omaa nyt alalinjan ET.1

 https://github.com/cov-lineages/pango-designation/issues/1732

BQ.1.1.35 sublineage with S:K182N(A22108T) mainly in UK (186 seqs) #1732

 

 Sitaatti  a) tutkijan antamasta sekvenssin esittelystä GITHUB:iin

sekä Master/ designaatiolinkistä  MILESTONE:  ET.1  designaatiosta  eilen.

 

a)  "Defining mutations: BQ.1.1.35>T9619C>A22108T (S:K182N)
GISAID query: Spike_R346T, Spike_K444T, Spike_F486V, Spike_K147E, Spike_K182N
Cov-spectrum query: BQ.1.1.35 + S:K182N
Earliest seq: 2022-11-23 (Netherland, EPI_ISL_16202528)
Most recent seq: 2023-02-21 (Austria, EPI_ISL_17082550)
Countries Detected: UK (130), Austria (19), Belgium (14), Netherland (9), Germany (8), France (4), Finland (1), Sweden (1)"

 "When I proposed the CH.1.1 sublineage with S:K182N (#1726), I noted lots of Pangolin "unassigned" sequences with S:K444T, S:L452R and S:K182N. Some of them were of CH.1.1+S: K182N sublineage, but others were BA.5-like Spike. Now Usher tree confirms that most of them belong to sublineage of BQ.1.1.35 (BQ.1.1+S:K147E).
(S: K182N mutation is based on nuc: A22108T in this BQ.1.1.35 sublineage, while A22108C in CH.1.1+S: K182N sublineage). 

Cov-spectrum relative growth rate shows slight advantage to parent lineage (BQ.1.1.35)".

 

b)   (cov-lineages/pango-designation#1766)    

Added new lineage ET.1 from cov-lineages#1732 with 152 new sequence designations, and 32 updated from BQ.1.1.35