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torsdag 2 juli 2020

PPIL3 ( syklofiliini J) Ja FKBP7 -10 ja -15 peptidyyliproliini cis-trans-isomeraasit ovat SARS2 virus interaktioproteiineja

  •  PPIL3, (2q33.1) cyclophilin J, CYPJ 

(SARS2 nsp12:n interaktioproteiini) 
https://www.genecards.org/cgi-bin/carddisp.pl?gene=PPIL3&keywords=PPIL3

 Aliases for PPIL3 Gene
Peptidylprolyl Isomerase Like 3 2 3 5
Cyclophilin J 2 3 4
Peptidylprolyl Isomerase (Cyclophilin)-Like 3 2 3
Peptidyl-Prolyl Cis-Trans Isomerase-Like 3 3 4
Cyclophilin-Like Protein PPIL3 3 4
Rotamase PPIL3 3 4
EC 5.2.1.8 4 52
PPIase 3 4
Peptidylprolyl Cis-Trans Isomerase-Like Protein 3 3
Cyclophilin-Like Protein 3 3
PPIase-Like Protein 3 3
CYPJ 3
CyPJ 4
PPIL3 Gene: This gene encodes a member of the cyclophilin family. Cyclophilins catalyze the cis-trans isomerization of peptidylprolyl imide bonds in oligopeptides. They have been proposed to act either as catalysts or as molecular chaperones in protein-folding events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2008]
Summary for PPIL3 Gene: Peptidylprolyl Isomerase Like 3  is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include peptidyl-prolyl cis-trans isomerase activity. An important paralog of this gene is PPIL2.
PPIases accelerate the folding of proteins. PPIL3  catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing. PPIL3_HUMAN,Q9H2H8
  • FKBP15, (9q32),  FK506-Binding Protein 15

( SARS2 nsp2 interaktioproteiini)  
https://www.genecards.org/cgi-bin/carddisp.pl?gene=FKBP15&keywords=FKBP15
Aliases for FKBP15 Gene
FKBP Prolyl Isomerase 15 2 3 5
KIAA0674 2 3 4
Protein Phosphatase 1, Regulatory Subunit 76 2 3
FK506 Binding Protein 15, 133kDa 2 3
133 KDa FK506-Binding Protein 3 4
WASP And FKBP-Like Protein 2 3
FK506-Binding Protein 15 3 4
133 KDa FKBP 3 4
FKBP-133 3 4
FKBP-15 3 4
WAFL 3 4
FK506-Binding Protein 133kDa 3
WASP- And FKBP-Like Protein 4
FK506 Binding Protein 15 2
FKBP133 3
PPP1R76 3
FKBP15 Gene: FKBP Prolyl Isomerase 15 is a Protein Coding gene. Diseases associated with FKBP15 include Megalencephalic Leukoencephalopathy With Subcortical Cysts 1 and Spinocerebellar Ataxia 11. Gene Ontology (GO) annotations related to this gene include actin binding and peptidyl-prolyl cis-trans isomerase activity. An important paralog of this gene is FKBP9.
FKBP15 Gene n ay be involved in the cytoskeletal organization of neuronal growth cones. Seems to be inactive as a PPIase (By similarity). Involved in the transport of early endosomes at the level of transition between microfilament-based and microtubule-based movement. FKB15_HUMAN,Q5T1M5

  • FKBP10, ( 17q21.2), Peptidyl-Prolyl Cis-Trans Isomerase FKBP10 

https://www.genecards.org/cgi-bin/carddisp.pl?gene=FKBP10&keywords=FKBP10
 (SARS2 ORF8  proteiinin interaktioproteiini)
FK506 binding proteinb 10
https://www.genecards.org/cgi-bin/carddisp.pl?gene=FKBP10&keywords=FKBP10
Aliases for FKBP10 Gene
FKBP Prolyl Isomerase 10 2 3 5
Peptidyl-Prolyl Cis-Trans Isomerase FKBP10 3 4
FK506 Binding Protein 10, 65 KDa 2 3
65 KDa FK506-Binding Protein 3 4
FK506-Binding Protein 10 3 4
Immunophilin FKBP65 3 4
PPIase FKBP10 3 4
65 KDa FKBP 3 4
EC 5.2.1.8 4 52
Rotamase 3 4
FKBP-10 3 4
FKBP-65 3 4
FKBP65 3 4
FK506 Binding Protein 10 (65 KDa) 2
FK506 Binding Protein 10 2
HFKBP65 3
PPIASE 3
BRKS1 3
OI11 3
OI6 3
FKBP10 Gene: The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. This protein localizes to the endoplasmic reticulum  (ER) and acts as a molecular chaperone. Alternatively spliced variants encoding different isoforms have been reported, but their biological validity has not been determined.[provided by RefSeq, Nov 2009]
GeneCards Summary for FKBP10 Gene
FKBP10 (FKBP Prolyl Isomerase 10) is a Protein Coding gene. Diseases associated with FKBP10 include Bruck Syndrome 1 and Osteogenesis Imperfecta, Type Xi. Gene Ontology (GO) annotations related to this gene include calcium ion binding and FK506 binding. An important paralog of this gene is FKBP9.
UniProtKB/Swiss-Prot Summary for FKBP10 Gene
PPIases accelerate the folding of proteins during protein synthesis. FKB10_HUMAN,Q96AY3 

FKBP7 , (2q33.1), Peptidyl-Prolyl Cis-Trans Isomerase FKBP7
(SARS2 ORF8 ineraktioproteiini) 
Aliases for FKBP7 Gene
FKBP Prolyl Isomerase 7 2 3 5
Peptidyl-Prolyl Cis-Trans Isomerase FKBP7 3 4
23 KDa FK506-Binding Protein 3 4
FK506 Binding Protein 7 2 3
FK506-Binding Protein 7 2 4
PPIase FKBP7 3 4
23 KDa FKBP 3 4
Rotamase 3 4
FKBP-23 3 4
FKBP-7 3 4
FKBP23 3 4
FK506-Binding Protein 23 3
EC 5.2.1.8 4
PPIase 3
FKBP7 Gene: The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. Members of this family exhibit PPIase activity and function as molecular chaperones. A similar protein in mouse is located in the endoplasmic reticulum and binds calcium. [provided by RefSeq, Jul 2008]
FKBP7 (FKBP Prolyl Isomerase 7) is a Protein Coding gene. Diseases associated with FKBP7 include Cerebellar Ataxia, Cayman Type. Gene Ontology (GO) annotations related to this gene include calcium ion binding and FK506 binding. An important paralog of this gene is FKBP14.
Summary for FKBP7 Gene PPIases accelerate the folding of proteins during protein synthesis. FKBP7_HUMAN,Q9Y680

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