LÄHDE:
http://www.ncbi.nlm.nih.gov/pubmed/25142600
J Virol. 2014 Aug 20. pii: JVI.01863-14. [Epub ahead of print]Analysis of the highly diverse gene borders in Ebola virus reveals a distinct mechanism of transcriptional regulation.
http://www.ncbi.nlm.nih.gov/pubmed/25142600
J Virol. 2014 Aug 20. pii: JVI.01863-14. [Epub ahead of print]Analysis of the highly diverse gene borders in Ebola virus reveals a distinct mechanism of transcriptional regulation.
Brauburger K1, Boehmann Y2 et al.
Ebola virus (EBOV) belongs to the group of nonsegmented negative sense RNA viruses.
The seven EBOV genes are separated by variable gene borders, including short (4-5 nucleotides) intergenic regions (IRs), a single long (144 nucleotides) IR and gene overlaps, where the neighboring gene end and start signals share five conserved nucleotides. The unique structure of the gene overlaps and the presence of a single long IR are conserved among all filoviruses.
The seven EBOV genes are separated by variable gene borders, including short (4-5 nucleotides) intergenic regions (IRs), a single long (144 nucleotides) IR and gene overlaps, where the neighboring gene end and start signals share five conserved nucleotides. The unique structure of the gene overlaps and the presence of a single long IR are conserved among all filoviruses.
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