Muista silloij minua, kun punkki puree sinua. (Vanha suomalainen sanonta)
Punkin puremaa EI tunne eikä sitä huomaa, koska punkkisykki on niin puuduttavaa ainetta, mutta purematunne kestää kauan kuin skorpionin pisto eikä puremapaikan tuntoaistums katoa viikkoihin ehkä pitempikin aika kuluu ja puremakohta tuntuu kutiavalta ja pistävältä, aikka siitä olisi poistanut silmillänähtään punkkimateriaalin. Punkin sylki ja puremajärjestelmä ovat tämän takia kiinostavia.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211429/
Published online 2007 Sep 25. doi: 10.1016/j.ibmb.2007.09.003
PMCID: PMC2211429
NIHMSID: NIHMS37009
Comparative sialomics between hard and soft ticks: Implications for the evolution of blood-feeding behavior
Author information ► Copyright and License information ►
Abstract
Ticks
evolved various mechanisms to modulate their host’s hemostatic and
immune defenses. Differences in the anti-hemostatic repertoires suggest
that hard and soft ticks evolved anti-hemostatic mechanisms
independently, but raise questions on the conservation of salivary gland
proteins in the ancestral tick lineage. To address this issue the
sialome (salivary gland secretory proteome) from the soft tick, Argas monolakensis
was determined by proteomic analysis and cDNA library construction of
salivary glands from fed and unfed adult female ticks. The sialome is
composed of ~130 secretory proteins, of which the most abundant protein
folds are the lipocalin, BTSP, BPTI and metalloprotease families which
also comprise the most abundant proteins found in the salivary glands.
Comparative analysis indicates that the major protein families are
conserved in hard and soft ticks. Phylogenetic analysis shows, however,
that most gene duplications are lineage specific, indicating that the
protein families analyzed possibly evolved most of their functions after
divergence of the two major tick families. In conclusion, the ancestral
tick may have possessed a simple (few members for each family), but
diverse (many different protein families) salivary gland protein domain
repertoire.
Keywords: Argas, blood-feeding, evolution, proteome, sialome
Siirryn tästä metalloproteaasiblogiini MMP.
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