WHO lähteestä 26.11. 2023 muistiin covid-tilanteesta VOI ja VUM-variantit (21.11. 2023)

Note: To better reflect the current variant landscape, which is dominated by Omicron descendent lineages, WHO updated its tracking system and working definitions of VOCs and VOIs on 15 March 2023.

4 October 2023

Updated working definitions and primary actions for SARS-CoV-2 variants

Currently circulating variants of interest (VOIs) (as of 21 November 2023)

 

Pango lineage	Nextstrain clade	Genetic features	Earliest documented samples	Date of designation and risk assessments
XBB.1.5	23A	Recombinant of BA.2.10.1 and BA.2.75 sublineages, i.e. BJ.1 and BM.1.1.1, with a breakpoint in S1.  XBB.1 + S:F486P (similar Spike genetic profile as XBB.1.9.1)	21-10-2022	11-01-2023 XBB.1.5 Rapid Risk Assessment, 11 January 2023 XBB.1.5 Updated Rapid Risk Assessment, 25 January 2023 XBB.1.5 Updated Risk Assessment, 24 February 2023 XBB.1.5 Updated Risk Assessment, 20 June 2023
XBB.1.16	23B	Recombinant of BA.2.10.1 and BA.2.75 sublineages, i.e. BJ.1 and BM.1.1.1 XBB.1 + S:E180V, S:K478R and S:F486P	09-01-2023	17-04-2023 XBB.1.16 Initial Risk Assessment, 17 April 2023 XBB.1.16 Updated Risk Assessment, 05 June 2023
EG.5	Not assigned	XBB.1.9.2 + S:F456L Includes EG.5.1: EG.5 + S:Q52H HK.3: EG.5 + S:Q52H, S:L455F HV.1: EG.5 + S:Q52H, S:F157L, S:L452R	17-02-2023	09-08-2023 EG.5 Initial Risk Evaluation, 09 August 2023 EG.5 Updated Risk Evaluation, 21 September 2023 EG.5 Updated Risk Evaluation, 21 November 2023
BA.2.86	Not assigned	Mutations relative to BA.2 Includes JN.1: BA.2.86 + S:L455S	24-07-2023	21-11-2023 BA.2.86 Initial Risk Evaluation, 21 November 2023

 

Currently circulating variants under monitoring (VUMs) (as of 21 November 2023)

 

Pango lineage	Nextstrain clade	Genetic features	Earliest documented samples	Date of designation and risk assessments
DV.7	23C	CH.1.1 +  S:N185D, S:L858I	19-01-2023	23-10-2023
XBB*	22F	BA.2+ S:V83A, S:Y144-, S:H146Q, S:Q183E, S:V213E, S:G252V, S:G339H, S:R346T, S:L368I, S:V445P, S:G446S, S:N460K, S:F486S, S:F490S	19-08-2022	12-10-2022
XBB.1.9.1	23D	Recombinant of BA.2.10.1 and BA.2.75 sublineages, i.e. BJ.1 and BM.1.1.1 XBB.1 + S:F486P (similar Spike genetic profile as XBB.1.5)	05-12-2022	30-03-2023
XBB.1.9.2#	23D	Recombinant of BA.2.10.1 and BA.2.75 sublineages, i.e. BJ.1 and BM.1.1.1 XBB.1 + S:F486P, S:Q613H	05-12-2022	26-04-2023
XBB.2.3	23E	Recombinant of BA.2.10.1 and BA.2.75 sublineages, i.e. BJ.1 and BM.1.1.1 XBB + S:D253G, S:F486P, S:P521S	09-12-2022	17-05-2023

^* Excludes XBB sublineages listed here as VOIs and VUMs

^# Excludes XBB.1.9.2 sublineages listed here as VOIs and VUMs