Uusi linja XAC saanut virstanpylväänsä (milestone)

Tämä rekombinantti muodostuu mahdollisesti  linjojen  BA.2.75* ja BQ.1* kesken.

https://github.com/cov-lineages/pango-designation/issues/1752

agamedilab  commented Mar 11, 2023

Proposal for a potential BA.2.75*/BQ.1*recombinant sublineage
Earliest sequence: 22.12.2022 (Singapore)
Countries detected: Singapore, Malaysia, USA, England, Austria

This is another potiential BA.2.75*/BQ.1* recombinant sublineage defined by S:D111N, ORF1ab:T1828N, ORF3a:S195P. Nextclade identifies the sequences as XBP or XBS while usher places them within BA.2.75. 42 seq. as of 11.03.23.

Gisaid query: C5748A, T13324C, G21893A, C22747T, T25975C

Defining Mutations:
nuc unique C5748A, T13324C, G21893A, C22747T, T25975C
nuc homoplasies C11124T, C23595T
ORF1ab unique T1828N
ORF1ab homoplasies A3620V
S unique D111N
S homoplasies T678I
ORF3a unique S195P

 . We've added lineage XCA with 41 newly designated sequences, and 0 updated. 

Defining mutations C5748A (ORF1a:T1828N), C11124T (ORF1a:A3620V), T25975C (ORF3a:S195P), G21893A (S:D111N), C23595T (S:T678I), T13324C, C22747T (following G18583A (ORF1b:V1706I)).

 

 --LISÄYS:

(Linkissä on USHER ja NEXTSTRAIN  kuvaajat) 

(Tällä linjalla XCA  on alakladi, joka saanee siten oman linjanimensä myöhemmin. sen aminohappomuutos kuvataan myös linkissä :  "Small subclade defined by ORF1ab: T749A, P7013L, R7014H, R7014S (11 seq., England) maybe worth proposing on its own.ORF1b:P2612L ORF1b:R2613N ")