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söndag 21 augusti 2016

ZIKA-virus genomeja selvitetty ainakin kolme toisistaan eriävää kantaa

Genome Announc. 2016 Aug 18;4(4). pii: e00800-16. doi: 10.1128/genomeA.00800-16.

Complete Genome Sequences of Three Historically Important, Spatiotemporally Distinct, and Genetically Divergent Strains of Zika Virus: MR-766, P6-740, and PRVABC-59.

Yun SI1, Song BH1, Frank JC1, Julander JG1, Polejaeva IA1, Davies CJ1, White KL1, Lee YM2


Here, we report the 10,807-nucleotide-long consensus RNA genome sequences of three spatiotemporally distinct and genetically divergent Zika virus strains, with the functionality of their genomic sequences substantiated by reverse genetics
 MR-766 (African lineage, Uganda, 1947),
 P6-740 (Asian lineage, Malaysia, 1966),
 and PRVABC-59 (Asian lineage-derived American strain, Puerto Rico, 2015).

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