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måndag 9 mars 2020

COVID-19 nsp9 ( 4141..4253), 113 aminohappoa; ssRNA:ta sitova proteiini

  mat_peptide     4141..4253
                     /product="nsp9"
                     /note="ssRNA-binding protein; produced by both pp1a and
                     pp1ab"
 
https://www.ncbi.nlm.nih.gov/protein/YP_009725305.1 
FEATURES             Location/Qualifiers
     source          1..113
                     /organism="Severe acute respiratory syndrome coronavirus
                     2"
                     /isolate="Wuhan-Hu-1"
                     /host="Homo sapiens"
                     /db_xref="taxon:2697049"
                     /country="China"
                     /collection_date="Dec-2019"
     Protein         1..113
                     /product="nsp9"
                     /note="ssRNA-binding protein; produced by both pp1a and
                     pp1ab"
                     /calculated_mol_wt=12378
     Precursor       1..113
                     /derived_from="YP_009724389.1:4141..4253"
ORIGIN      
        1 nnelspvalr qmscaagttq tactddnala yynttkggrf vlallsdlqd lkwarfpksd
       61 gtgtiytele ppcrfvtdtp kgpkvkylyf ikglnnlnrg mvlgslaatv rlq
//

 
 COVID-19
 
4141 nnelspvalr qmscaagttq tactddnala yynttkggrf vlallsdlqd lkwarfpksd
     4201 gtgtiytele ppcrfvtdtp kgpkvkylyf ikglnnlnrg mvlgslaatv rlq 


Vanha Sars 2003 
4118.. 4230) 
nne lspvalrqms caagttqtac
     4141 tddnalayyn nskggrfvla llsdhqdlkw arfpksdgtg tiyteleppc rfvtdtpkgp
     4201 kvkylyfikg lnnlnrgmvl gslaatvrlq
 
Vaihtuneita aminohappoja havaitsen: 
Vanha SARS
4151 N     vaihtunut:  4174 T  (asparagiini thrreoniiniksi)
4152 S     vaihtunut:  4175 T  (seriini threoniiniksi)
4165 H     vaihtunut:  4188 L   (histidiini leusiiniksi, tuotti tumareseptorin)

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