http://www.ncbi.nlm.nih.gov/pubmed/23446374
TIM-1 is the T- cell receptor for PtdSer = The senescent cell gives to T-Cell a message: "Find me and eat me". T Cell begins to make a program and execute it.
So T Cell system also begin to give messages among immune system cells (Cell mediated immunity,) for this silent cleaning up among tissue cells: called apoptosis, which is a.programmed cell death without inflammation
When Ebola gives that kind of signals PtdSer , T-Cells are thus utterly distracted and loses the important timing and exactness. When Ebola virus is budding, the membrane is shedding microvesicles with microparticles: There are many PtdSer in those particles. They not only distract T-Cells but cause coagulopathia, even DIC, because TF also is found in microparticles.
EBOV is faking by apoptosis mimicry.
Look :E.g. Activated Thrombocyte uses PtdSer: expression on their surface as a potent tool in thrombogenesis. But then the individual platelet is soon going to disappear.
http://www.hindawi.com/journals/ah/2012/384685/
For example, platelets (particularly activated platelets) accelerate coagulation by providing a negatively charged phosphatidylserine- (PS-) rich membrane surface that enhances the generation of thrombin, which converts fibrinogen (Fg) to fibrin [16, 17].
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